Mucosal Immunology Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization Pubmed: 31086271 The role of amniotic fluid exosome, hypoxia inducible fator-1α, and inflammatory cytokine in cervical insufficiency pharmacological research Neuroprotection in non-...
The aim of our work was to reveal BDQ effects on the functional activity of pro-inflammatory (M1) human macrophages.BDQ effects (5 渭g/ml) were assessed at different stages of M1-macrophage differentiation (MD) which was induced in THP-1 monocytic cell line by 100 nM PMA. We used RT-...
In obese individuals, the increase of free fatty acids derived from disrupted adipocytes or their apoptosis results in the infiltration of classically activated macrophages (M1) (Carobbio et al., 2019, Ye, 2013). Adipose tissue macrophage produces TNF-α, IL-6 and other proinflammatory cytokines ...
Mucosal Immunology Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization Pubmed: 31086271 The role of amniotic fluid exosome, hypoxia inducible fator-1α, and inflammatory cytokine in cervical insufficiency pharmacological research Neuroprotection in non-...
In line with this, FK506 treatment clearly protected ECM integrity in vivo by markedly decreasing subchondral sclerosis, less development of subchondral pores, depletion of synovial macrophage activation and lower osteophyte growth. Conclusion: FK506 protected cartilage matrix integrity in vitro and in ...