此外,某些神经元表达IL-4Rα和IL-13Rα1,表明存在神经免疫联系。IL-13Rα2在非造血细胞中表达,并在某些癌细胞上过度表达;其在特应性疾病中的作用尚未得到充分探讨。 "Commonality of the IL-4/IL-13 pathway in atopic diseases." Expert Rev Clin Immu***,2007. 13(5): 425-437. ...
In certain embodiments, a plasma cell ablating agent such as an anti-BCMA/anti-CD3 bispecific antibody ablates the plasma cells, including IgE+ plasma cells, while the IL-4/IL-13 pathway inhibitor prevents the generation of new IgE+ plasma cells, thus eliminating allergen-specific IgE in the...
The COVID-19 fatality rate is high when compared to the H1N1pdm09 (pandemic Influenza A virus H1N1 subtype) rate, and although both cause an aggravated inflammatory response, the differences in the mechanisms of both pandemic pneumonias need clarification. Thus, our goal was to analyze tissue ...
Polymorphisms in IL-4/ IL-13 pathway genes and glioma risk: An updated meta-analysis. Tumour Biol 2015; 36(1): 121-7.CHEN P Q, CHEN C, CHEN K, et al. Polymor- phisms in IL-4/IL-13 pathway genes and glioma risk: an updated meta-analysis [J]. Tumor Biol, 2014, 36 (1):...
Prenatal oxidative balance might influence cord blood IgE (cIgE) levels. We aimed to explore if certain prenatal dietary sources of antioxidants and pro-oxidants are associated with cIgE elevation and if they interact with IL4 and IL13 pathway genes. A s
小鼠白介素13(IL13)检测试剂盒相关产品如下:hz-E10073 中文名称:人组织因子途径抑制物(TFPI)ELISA试剂盒 英文名称:Human Tissue factor pathway inhibitor,TFPI ELISAkit 规格:48T/96Thz-E10074 中文名称:人干扰素诱导蛋白10(IP-10/CXCL10)ELISA试剂盒 英文名称:Human interferon-inducible protein 10,IP-10 ELIS...
Resveratrol is a polyphenolic compound showing anti-inflammatory activity by inhibition of high mobility group box 1 cytokine responsible for the activation of nuclear factor-κB pathway in atopic dermatitis. To evaluate the efficacy of resveratrol through topical route we have developed resveratrol-loaded...
GandhiNA, PirozziG, GrahamNMH. Commonality of the IL-4/IL-13 pathway in atopic diseases.Expert Rev Clin Immunol. 2017;13(5):425–437.28277826 PubMedWeb of Science ®Google Scholar JunttilaIS, CreusotRJ, MoragaI, et al. Redirecting cell-type specific cytokine responses with engineered interleu...
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(IGF-1) levels. Subsequent investigations unveiled that gut-derived IL-13 stimulated the production of hepatic IGF-1 by activating the IL-13R/Jak2/Stat6 pathway in vitro. The IGF-1 levels were increased in the muscles, leading to an upregulation of and resulted the increased genes associated...