Previous study has reported that IL-4-mediated enhanced aerobic glycolysis is essential for M2 macrophage activation [13]. THP1 cells and U937 cells were stimulated by PMA combined with or without IL-4 for 48 h (Supplementary Fig.5A). The results of qRT-PCR showed that the expression of ...
Macrophage polarization to M1 or M2 activation status may determine the progression or resolution of the inflammatory response. We have previously reported that cardiotrophin-1 (CT-1) displays both cytoprotective and metabolic activities. The role of CT-1 in inflammation remains poorly understood. Here...
Macrophages are a highly adaptive population of innate immune cells. Polarization withIFNγandLPSinto the “classically activated” M1 macrophage enhances pro-inflammatory and microbicidal responses, important for eradicating bacteria such as Mycobacterium tuberculosis. By contrast, “alternatively activated” ...
Gao, S. et al. Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13.J. Mol. Cell. Cardiol.85, 131–139 (2015). ArticleCASGoogle Scholar Hou, J. et al. An interleukin-4-induced transcription factor: IL-4 Stat.Science265, 1701–1706 (1994). ArticleCASGoogle Scho...
Correction to: TSPO Modulates IL-4-Induced Microglia/Macrophage M2 Polarization Via PPAR-γ PathwayThe original version of this article unfortunately contained mistakes in the Author Group section. Authors Dandan Zhou and Lei Ji were assigned to incorrect institutions....
IL-4 administration restored in eosinophil-depleted mice PI- and AI-regions, normalized neutrophil numbers, efferocytosis, M2-macrophage polarization as well as resolution of zymosan-induced hypersensitivity. In conclusion, IL-4-expressing eosinophils support the resolution of inflammation by enabling the ...
Fig. 6. OxLDL-treated plasma cells accelerate M2 macrophage polarization. (A) The frequencies of CD138+ plasma cells and the expression levels of IL-4 were analyzed by flow cytometric (n = 4 mice per group). (B) The levels of IL-4 in plasma cell supernatant were analyzed by ELISA...
"Interleukin-4-Loaded Heparin Hydrogel Regulates Macrophage Polarization to Promote Osteogenic Differentiation"（ACS Biomaterials Science & Engineering, 2024）——该研究采用Elabscience IL-4抗体评估巨噬细胞极化对骨再生的影响。Elabscience® APC Anti-Mouse IL-4 Antibody 抗体通过靶向 IL-4，助力研究者在单...
Favipiravir ameliorates bleomycin-induced pulmonary fibrosis by reprogramming M1/M2 macrophage polarization Authors - Ruiqin Zhang View Article mouse Int Immunopharmacol Emu oil alleviates atopic dermatitis-like responses by inhibiting Cdc42 signaling of keratinocyte Authors - Lingwei Bu View Article pig WB...
cells after IL.4 仃 eatment. 4)SUMOylation of KLF4 promotes IL-4 treated BMDM M2 polarization. Key words:KLF4 SUMOylation macrophage polarization 6 万方数据 大连医科大学硕士学位论文 KLF4 的 SUMO 化修饰促进 I L-4 诱导巨噬细胞向 M2 型极 化 硕士研究生姓名:王克洲 指导教 师:邢嵘教授 程金...