PD-1 antibody therapy in gastric cancer. These findings highlight the role of IL-4-induced macrophage polarization and metabolic reprogramming in immune resistance and verify IL-4 as potential targets for improving treatment outcomes in gastric cancer patients. Similar content being viewed by others H...
Macrophages are a highly adaptive population of innate immune cells. Polarization withIFNγandLPSinto the “classically activated” M1 macrophage enhances pro-inflammatory and microbicidal responses, important for eradicating bacteria such as Mycobacterium tuberculosis. By contrast, “alternatively activated” ...
Macrophage polarization to M1 or M2 activation status may determine the progression or resolution of the inflammatory response. We have previously reported that cardiotrophin-1 (CT-1) displays both cytoprotective and metabolic activities. The role of CT-1 in inflammation remains poorly understood. Here...
Fig. 6. OxLDL-treated plasma cells accelerate M2 macrophage polarization. (A) The frequencies of CD138+ plasma cells and the expression levels of IL-4 were analyzed by flow cytometric (n = 4 mice per group). (B) The levels of IL-4 in plasma cell supernatant were analyzed by ELISA...
Correction to: TSPO Modulates IL-4-Induced Microglia/Macrophage M2 Polarization Via PPAR-γ PathwayThe original version of this article unfortunately contained mistakes in the Author Group section. Authors Dandan Zhou and Lei Ji were assigned to incorrect institutions....
Gao, S. et al. Curcumin induces M2 macrophage polarization by secretion IL-4 and/or IL-13.J. Mol. Cell. Cardiol.85, 131–139 (2015). ArticleCASGoogle Scholar Hou, J. et al. An interleukin-4-induced transcription factor: IL-4 Stat.Science265, 1701–1706 (1994). ...
IL-4 administration restored in eosinophil-depleted mice PI- and AI-regions, normalized neutrophil numbers, efferocytosis, M2-macrophage polarization as well as resolution of zymosan-induced hypersensitivity. In conclusion, IL-4-expressing eosinophils support the resolution of inflammation by enabling the ...
"Dimethyl fumarate alleviates allergic asthma by strengthening the Nrf2 signaling pathway in regulatory T cells"（Frontiers in Immunology, 2024）——该研究使用Elabscience IL-4抗体分析哮喘模型中的Th2细胞极化。"Interleukin-4-Loaded Heparin Hydrogel Regulates Macrophage Polarization to Promote Osteogenic ...
Favipiravir ameliorates bleomycin-induced pulmonary fibrosis by reprogramming M1/M2 macrophage polarization Authors - Ruiqin Zhang View Article mouse Int Immunopharmacol Emu oil alleviates atopic dermatitis-like responses by inhibiting Cdc42 signaling of keratinocyte Authors - Lingwei Bu View Article pig WB...
cells after IL.4 仃 eatment. 4)SUMOylation of KLF4 promotes IL-4 treated BMDM M2 polarization. Key words:KLF4 SUMOylation macrophage polarization 6 万方数据 大连医科大学硕士学位论文 KLF4 的 SUMO 化修饰促进 I L-4 诱导巨噬细胞向 M2 型极 化 硕士研究生姓名:王克洲 指导教 师:邢嵘教授 程金...