M2 macrophagesImmunopathogenesisLacaziosis is a cutaneous chronic mycosis caused by Lacazia loboi. Macrophages are important cells in the host immune response in fungal infections. The macrophage population exhibits strong plasticity that varies according to the stimuli in the microenvironment of lesions ...
relation to tumor angiogenesis Wen-Qun Zhong1, Gang Chen1,2, Wei Zhang1,2, Xue-Peng Xiong1,2, Yi Zhao1,3, Bing Liu1,2 & Yi-Fang Zhao1,2 The purpose of this study was to evaluate the presence of M2-polarized macrophages and their relationships to angiogenesis in kera...
AIMS: During sepsis, macrophages are alternatively activated toward an M2-like phenotype on contact with apoptotic cells (ACs) or their secretion products. Simultaneously, NADPH oxidase-dependent reactive oxygen species (ROS) formation is attenuated, thus contributing to immune paralysis. However, the ...
Our results show that CC induce TFPI and cytokine expression in M2-polarized macrophages through activation of the ER stress pathway and that TFPI has a protective effect against TNF-α and IL-6 mediated inflammation. These mechanisms may have implications for the pathogenesis of atherosclerosis....
Macrophages are polarized into two functionally distinct forms, M1 and M2, in response to different microenvironment. Tumor-associated macrophages (TAMs) generally have M2 phenotype and promote tumor progression. Few studies to date have described the infiltration of M2-polarized macrophages in ovarian ...
Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells World Journal of Gastroenterology (2021) -4Comments doi: 10.3748/wjg.v27.i36.6079 issn: 1007-9327 pubmed: 34629821 Hai-Yan Cui,Jian-Sheng Rong,Ju Chen,Jie Guo,Jia-Qin Zhu,Mei Ruan,...
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Mantovani A, Sozzani S, Locati M et al (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes... A Mantovani,S Sozzani,M Locati,......
Murine bone marrow-derived macrophages (M0) and M1- and M2-polarized macrophages are being widely used as a laboratory model for polarized macrophages related molecular mechanism analysis. Gene expression analysis based on reference gene normalization using RT-qPCR was a powerful way to explore the ...
M2-polarized macrophages promote tumor growth and metastasis within the cancer ecosystemCancer continues to be the major cause of morbidity and death of more than 500,000 people in the U.S. annually. Alternatively activated macrophages (M2 macrophages or TAMs) can facilitate tumor invasiveness and ...
The purpose of this study was to evaluate the presence of M2-polarized macrophages and their relationships to angiogenesis in keratocystic odontogenic tumor (KCOT). M2-polarized macrophages were detected in KCOT samples by immunohistochemistry and immunofluorescence. Meanwhile, microvessel density measured...