癌症肺转移 文章:Briukhovetska et al., T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis,2023, Immunity 56, 143–161。 研究摘要 虽然T细胞可以发挥强大的抗肿瘤免疫作用,但在乳腺癌和肺癌中产生IL-22的T辅助细胞(Th)细胞...
2023年1月10日,来自德国慕尼黑大学附属医院的Sebastian Kobold团队在Immunity杂志上发表了一篇题为T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis的文章...
Two recent studies describe new roles for interleukin-22 (IL-22), an IL-10-family cytokine that is mainly produced by T helper 17 (T H 17) cells, in host defence at mucosal surfaces. Aujla et al . explored the role of IL-22 in a mouse model of pneumonia caused by infection with ...
近日,上海交通大学医学院附属第六人民医院胡承研究员、徐捷博士后、海军军医大学第二附属医院(上海长征医院)殷浩主任与复旦大学附属中山医院李晓牧主任在Cell Reports杂志上发表了题为Pancreatic β cell interleukin-22 receptor subunit alpha...
近日,发表在《Immunity》上,标题为:“T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis ”的文章中,揭示了Th细胞产生的IL-22会增加癌细胞中CD155的表达,通过促进激活受体CD226的内化来损害NK细胞功能,进而促进癌细胞转移。 尽管...
[9] Schmechel S., Konrad A., Diegelmann J., Glas J., Wetzke M., Paschos E., Lohse P., Göke B., Brand S. Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R...
[9] Schmechel S., Konrad A., Diegelmann J., Glas J., Wetzke M., Paschos E., Lohse P., Göke B., Brand S. Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R...
aAmerican society changes rapidly. 美国社会迅速地改变。[translate] aFurther understanding of the function and regulation of IL-22 would certainly be beneficial in the future treatment of IBD. 对IL-22的作用和章程的进一步理解一定在将来是IBD的有利治疗。[translate]...
Expression and function of IL-22 in rheumatoid arthritis-associated interstitial lung disease 引用 收藏 分享 摘要 目的观察IL-22在类风湿关节炎相关间质性肺病中(RA-ILD)的表达情况,建立动物模型探讨IL-22在肺纤维化中的作用。方法选择2021年10月—2022年10月在徐州医科大学附属医院初诊初治的类风湿关节炎...
Background:This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed...