内容提示: IL-2R b bIL-2R g gIL-2R a aPc-JunPPSTAT5NF- k k BPPc-Mycc-Fosc-JunElk1PJAK1I k k BDegradationAkt/PKBPathwaySHCGTPGeneExpressionCytokineProductionPIP2PTENLckDAGPLC- g gSTAT5NFATc-FosElk1MEKsIKKsRaf1Ca 2 +SOSGRB2ERKsPIP3CalcineurinJNKPI3KIL-2IL-2 PathwaySTAT5STAT5Pc-...
产品名称: HS IL-2 PATHWAY, FAST .0 订购此产品 供应商: Invitrogen 规格: EACH 目录价: 3283 库存状态: 三周到货 CAS编号: 应用范围: 生化试验 种属来源: 相关信息: TaqMan® Array, Human IL-2 Pathway, Fast 96-well These 96-well plates are pre-configured with the most appropriate Taq...
1.theJanuskinase(JAK，两面神激酶)2.signaltransducerandactivatoroftranscriptionpathway （STAT，信号转导及转录激活因子)3.mitogen-activatedproteinkinase（MAPK,有丝分裂原活化蛋白激酶）4.phosphoinositide3-kinasesignaling JAK-STAT途径 二、IL-2在炎症反应中的促进作用 IL-2inthegenerationofeffectorandmemoryTcells ...
1.theJanuskinase(JAK，两面神激酶)2.signaltransducerandactivatoroftranscriptionpathway （STAT，信号转导及转录激活因子)3.mitogen-activatedproteinkinase（MAPK,有丝分裂原活化蛋白激酶）4.phosphoinositide3-kinasesignaling JAK-STAT途径 二、IL-2在炎症反应中的促进作用 IL-2inthegenerationofeffectorandmemoryTcells ...
ILC2 pathway can be activated by a variety of inflammatory factors and produce type 2 immune cytokines after tissue injury, thus participating in the pathophysiological process of tissue repair and promoting the formation of fibrosi...
2003. IL-2 activation of a PI3K-dependent STAT3 serine phosphorylation pathway in primary human T cells. Cell. Signal. 15:625-636.Fung, M. M., F. Rohwer, and K. L. McGuire. 2003. IL-2 activation of a PI3K- dependent STAT3 serine phosphorylation pathway in primary human T cells. ...
(IL-2Rγ) subunits, respectively. Both cell lines also feature a stable expression of the human JAK3 and STAT5 to obtain a fully functional IL-2 signaling pathway, as well as a STAT5-inducible secreted embryonic alkaline phosphatase (SEAP) reporter. The binding of IL-2 or IL-15 to ...
The interleukin (IL)-2 – IL-2 receptor (IL-2R) pathway is important in immunity, but is also involved in maintenance of self-tolerance. This paradox is further complicated by shedding of the IL-2Rα chain, revealing soluble (s)IL-2R. Binding of IL-2 to sIL-2R may either reduce ...
therapeutic potential of the programmed death-1ligand/programmed death-1pathway in human pancreatic cancer.clinical cancer research(2007);13:2151-2157;ohigashi,yuichiro等人,clinical significance of programmed death-1ligand-1and programmed death-1ligand 2expression in human esophagealcancer.clin.cancer ...
pathway positive regulation of B cell proliferation positive regulation of interferon-gamma production positive regulation of interleukin-17 production positive regulation of T cell proliferation positive regulation of activated T cell proliferation positive regulation of tyrosine phosphorylation of Stat5 protein...