12. Liu S, et al. Crystal structures of interleukin 17A and its complex with IL-17 receptor A[J]. Nat Commun. 2013;4:1888. 13. Lieu R, et al. Rapid and robust antibody Fab fragment crystallization utilizing edge...
[9]Wilson SC, Caveney NA, Yen M, et al. Organizing structural principles of the IL-17 ligand-receptor axis. Nature. 2022;609(7927):622-629. [10]Liu S, Song X, Chrunyk BA, et al. Crystal structures of interleu...
[2] Baker, Kevin James, Elizabeth Brint, and Aileen Houston. "Transcriptomic and functional analyses reveal a tumour-promoting role for the IL-36 receptor in colon cancer and crosstalk between IL-36 signalling and the IL-17/IL-23 axis." British Journal of Cancer 128.5 (2023): 735-747. [...
相关研究结果近期发表在Science Immunology期刊上,论文标题为“Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation”。论文通讯作者为清华大学医学院董晨(Chen Dong)教授。 这些研究人员在牛皮癣模型中发现IL-17RA/IL-17RD复合物在驱动IL-17...
在一项新的研究中,来自中国清华大学、华东师范大学和同济大学等研究机构的研究人员鉴定出第二个由IL-17RA 和IL-17RD 组成的IL-17R复合物(IL-17RA/IL-17RD),该复合物是由皮肤角质细胞表达的。相关研究结果近期发表在Science Immunology期刊上,论文标题为“Interleukin-17 receptor D constitutes an alternative recep...
[2] Baker, Kevin James, Elizabeth Brint, and Aileen Houston. "Transcriptomic and functional analyses reveal a tumour-promoting role for the IL-36 receptor in colon cancer and crosstalk between IL-36 signalling and the IL-17/IL-23 axis." British Journal of Cancer 128.5 (2023): 735-747. ...
Moligand™ 功能和特点 货号(SKU)包装规格是否现货价格数量 rp174282-500μg 500μg期货 原价:¥11,999.90 +- rp174282-1mg 1mg期货 原价:¥19,999.90 +- 大包装询价添加到收藏夹比较DATASHEET 查看相关系列 Interleukin-17 receptor Agonist (3) ...
1、Goepfert, A., S. Lehmann, J. Blank, F. Kolbinger, and J. M. Rondeau. 2020. Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling, IMMUNITY, 52: 499-512 e5. doi: 10.1016/j.immuni.2020.02...
[4]. Wright JF, et al. The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex. J Immunol. 2008 Aug 15;181(4):2799-805. [5]. Kinoshita H, et al. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stim...
2020. Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling, IMMUNITY, 52: 499-512 e5. doi: 10.1016/j.immuni.2020.02.004. 2、Amatya N, Garg A V, Gaffen S L. IL-17 signaling: the yin and the ...