IL-15 主要由单核细胞和巨噬细胞产生,与反应细胞上的 IL-15 受体(IL-15 receptor, IL-15R)结合,具有介导 T 细胞、NK(natural killer)细胞和 B 细胞增殖与活化,诱导细胞毒性淋巴细胞(cytotoxic T lymphocyte, CTL)产生等作用。IL-15 在抗肿瘤、自身免疫性疾病...
il-15 receptor:(il-15受体) 下载积分: 1500 内容提示: IL-15 ReceptorThomas A. Waldmann * and Yutaka TagayaMetabolism Branch, National Cancer Institute, NIH Building 10, Room 4N115, 10 Center Drive,MSC 1374, Bethesda, MD 20892-1374, USA*corresponding author tel: 301-496-6653, fax: 301-...
2.Jakobisiak M, Golab J, Lasek W, et al. Interleukin 15 as a promising candidate for tumor immunotherapy[J]. Cytokine & Growth Factor Reviews, 2011, 22(2): 99-108. 3.Lodolce J P, Boone D L, Chai S, et al. IL-15 Receptor Maintains Lym...
3.IL-15 Superagonist NAI in BCG-Unresponsive Non–Muscle-Invasive Bladder Cancer | NEJM Evidence 4.ImmunityBio Announces FDA Approval of ANKTIVA®, First-in-Class IL-15 Receptor Agonist for BCG-Unresponsive Non-Muscle Invasive Bladder Cancer - ImmunityBio, Inc.
[5] Mortier E, Quéméner A, Vusio P, Lorenzen I, Boublik Y, Grötzinger J, Plet A, Jacques Y. Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion prot...
SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis Cellular and Molecular Immunology; IF:24.100; DOI: 10.1038/s41423-023-01078-x 内容概要:研究发现SEL1L缺失会导致成熟T细胞数量和频率的显著降低,尤其是影响了CD8+ T细胞的稳...
Human interleukin 15 receptor subunit alpha ELISA Kit 产品规格: 96T 发货周期: 1～3天 产品价格: 询价 本产品仅可用于科研实验,严禁用于其他非科研用途! 组分规格数量 预包被抗人IL-15Rα抗体的96孔板96T1板 重组人IL-15Rα标准品(冻干)10ng/管2管 ...
Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not ...
药物名称:BNZ-1 (PEGylated peptide antagonist that binds to the common gamma chain (γc) signaling receptor for the cytokines interleukin (IL)-2, IL-9, and IL-15) 临床试验: NCT03239392 A Dose-Ranging Study of IV BNZ-1 in LGL Leukemi...
小鼠白介素15(IL15)检测试剂盒同类产品推荐:XY-E30661 【中文名称】大鼠骨成型蛋白受体Ⅱ(BMPR-Ⅱ)ELISA试剂盒品牌 【英文名称】Rat Bone morphogenetic protein receptor Ⅱ,BMPR-Ⅱ ELISA试剂盒多少钱 XY-E30662 【中文名称】大鼠骨成型蛋白受体1A(BMPR-1A)ELISA试剂盒品牌 【英文名称】Rat Bone morphogenetic pr...