IL-15 RECEPTOR Α & IL-15 FUSION蛋白 CBNumber: CB59738341 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商2 IL-15 RECEPTOR Α & IL-15 FUSION蛋白化学性质 安全信息 IL-15 RECEPTOR Α & IL-15 FUSION蛋白性质、用途与生产工艺 ...
An interleukin (IL)-15 superagonist/IL-15 receptor 卤 fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor activity in several in vivo studies. This in vitro study investigated the efficacy of IL-15SA...
Soiffer RJ, Murray C, Shapiro C, Collins H, Chartier S, Lazo S, Ritz J. Expansion and manipulation of natural killer cells in patients with metastatic cancer by low-dose continuous infusion and intermittent bolus...
IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients. J Transl Med. 2015 Apr 14;13:120. PMID: 25889680.Strengell M, Matikainen S, Sirén J, Lehtonen A, Foster D, Julkunen I, Sareneva T. IL-21 in synergy with IL-15 or IL-...
英文名称: Recombinant Human IL-15 Receptor α & IL-15 Fusion Protein 英文同义词: Recombinant Human IL-15 Receptor α & IL-15 Fusion Protein CAS号: 分子式: 分子量: 0 EINECS号: Mol文件: Mol File IL-15 RECEPTOR Α & IL-15 FUSION蛋白 信息错误报告 提交 按...
IL-15 receptor,12or is secreted in a soluble form upon cleavage of the transmembrane domain of the IL-15Rα.13Indeed, the circulating form of IL-15 in biological fluids is in complex with soluble IL-15Rα (sIL-15Rα) in both mice and humans.14Several studies in mice showed that the ...
“The ExpiCHO system helps speed up our developmental timelines by eliminating the need to have different hosts for transient versus stable expression. This eliminates a key quality risk when we transition from research into development.”Biot...
从头设计的IL-2模拟物Neoleukin-2/15 (Neo-2/15) 通过激活IL-2Rβ和IL-2Rγ再现IL-2和IL-15的免疫刺激功能【4-6】。与天然IL-2相比，这种模拟物通过避免优先激活CD25+免疫细胞以诱导有效的免疫治疗效果，同时降低毒性。然而，如果没有额外的定位策略，由于免疫细胞的靶向、非肿瘤激活导致的全身过度激活仍...
Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins. J Biol Chem. [6] Waldmann TA, Miljkovic MD, Conlon KC. Interleukin-15 (dys)regulation of lymphoid ...
Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients. J Transl Med. 2015 Apr 14;13:120. PMID: 25889680. Strengell M, Matikainen S, Sirén J, Lehtonen A, Foster D, Julkunen I, Sareneva T....