白细胞介素 12 受体（Interleukin - 12 Receptor，IL - 12R）是一种细胞表面受体，在免疫系统中具有重要作用，以下是其结构、功能、信号转导及与疾病关系的相关介绍：结构 IL - 12R 属于细胞因子受体超家族，由 β1 和 β2 两个亚基组成。其中，β1 亚基主要负责与白细胞介素 12（IL - 12）结合，而 β2...
近日，来自斯坦福大学医学院的K. Christopher Garcia研究团队在Cell杂志上发表题为Structural basis for IL-12 and IL-23 shared receptor usage reveals a gateway for shaping actions on T versus NK cells的研究论文，在这篇论文中，作者展示了完整的IL-12和IL-23受体复合物冷冻电镜（Cryo-EM）图谱，IL-12和I...
Igarashi O,Yamane H,Imajoh-Ohmi S,et al.IL-12 receptor (IL-12R) expression and accumulation of IL-12R beta 1 and IL-12R beta 2 mRNAs in CD4+ T cells by costimulation with B7-2 molecules. J Immunol . 1998Igarashi O, Yamane H, Imajoh-Ohmi S, Nariuchi H: IL-12 receptor (IL-...
IL-12 receptor is a heterodimer containing IL-12Rβ1 and IL-12Rβ2 subunits. Biology Area Immunology, Innate Immunity Molecular Family Cytokines/Chemokines Antigen References 1. Schoenhaut DS, et al. 1992. J. Immunol. 148:3433. 2. Manetti R, et al. 1994. J. Exp. Med. 179:12...
B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex, which is comprised of IL-12 Rβ1 and IL-12 Rβ2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells ...
Interleukin-12 receptor subunit beta-1 简称 IL-12 receptor subunit beta-1||IL-12R subunit 别名 CD212 其他名 IL-12 receptor beta componentCD_antigen: CD212 From Uniport IL-12 R beta 1/IL12RB1 基因家族蛋白 CD molecules 官方名通用名 ...
IL-12 is an essential cytokine involved in the generation of memory or memory-like NK cells. Mouse cytomegalovirus infection triggers NK receptor-induced, ligand-specific IL-12–dependent NK cell expansion, yet specific IL-1...
价格:元 规格: 10ug 50ug 联系方式:I47-825O-882O立刻购买 买家导航 IL12RB2细胞因子产品基本信息 产品名称: 重组小鼠白细胞介素-12受体亚基β2 产品又名: IL12RB2细胞因子, IL12RB2细胞因子 英文名称: IL12RB2; IL-12 receptor beta 2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12...
单克隆抗体与来自非人类灵长类动物的IL-12 (p70) 发生交叉反应。仅供研究使用(RUO)。不用于诊断过程。艾美捷抗人IL-12 (p70)单抗MT704文献参考：Pourakbari, B., et al. (2018). Evaluation of interleukin-12 receptor beta1 and interferon gamma receptor 1 deficiency in patients with disseminated BCG ...