IL-12 receptor. II. Distribution and regulation of receptor expression - Desai, Quinn, et al. - 1992 () Citation Context ... expressed on the surface of activated T cells that would be capable of modulating the T cell response to I1:12. Since PHA-activated T cells up-regulate ...
The expression levels of the genes for the interleukin-12 receptor (IL-12R) beta2 and IL-18Ralpha were reduced in both the NK cells and macrophages of B6-mi/mi mice, while the expression levels of the corresponding genes in B6-tg/tg mice were unaffected. The B6-mi/mi NK cells and ...
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function J Exp Med, 192 (11) (2000), pp. 1553-1562 View in ScopusGoogle Scholar 6 CH Kim, LS Rott, I Clark-Lewis, DJ Campbell, L Wu, EC Butcher Subspecialization of CXCR5+ T cells: B helper ac...
Antibodies to the IL-12 Receptor β2 Chain Mark Human Th1 But Not Th2 Cells In Vitro and In Vivo Great attention has been placed on the possibility of distinguishing Th1 from Th2 cells on the basis of differential expression of surface receptors. We have recently shown that the differential...
Recombinant Interleukin 11 Receptor Alpha (IL11Ra) [ PROPERTIES ]Source: Prokaryotic expressionHost: E.coliResidues: Trp59~Pro220Tags: N-terminal His TagSubcellular Location: MembranePurity: > 90%Traits: Freeze-dried powderBuffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, ...
In addition to the receptor expression, rapamycin upregulated the phosphorylation of STAT4 in both WT and IL-12RKO OT-I cells but not the expression of Janus-activated kinase 2 on the protein level (Figure 6a). This suggests that rapamycin directly enhances STAT4 activation during early ...
Therefore we investigated the IL-12 receptor beta(2) (IL-12R beta(2)) mRNA expression and RNA editing, nucleotide 2451 C-to-U conversion, to find the cause of low responsiveness to IL-12 in atopy. Quantitative real time PCR for mRNA expression and sequence analysis for RNA editing were ...
IL-23 is a heterodimeric cytokine that shares a subunit with IL-12 (IL-12B) along with an IL-23A (IL-23p19) subunit. Functionally, IL-12 increases the expression of vascular endothelial adhesion molecule-1 on the endothelium, directs leukocytes towards tumors and facilitates the ischemic-...
This is in contrast with the approach used here in which we narrowed the pleiotropic effects of IL-12 by leveraging differences in receptor expression across cell types and activation states. By limiting the activity of IL-12 to T cells, IL-12 partial agonists elicit anti-tumor activity ...
Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosis 来自 掌桥科研 喜欢 0 阅读量: 35 作者:U Müller,D Piehler,W Stenzel,G K?Hler,O Frey,J Held,A Grahnert,T Richter,M Eschke,T Kamradt ...