然而,脑出血后OPC铁死亡的调控机制尚不清楚。 白介素10(Interleukin-10,IL-10)主要由单核细胞、巨噬细胞和小胶质细胞等分泌,与其受体(IL-10 receptor,IL-10R)结合后激活JAK-STAT 信号通路而发挥作用[4]。已有研究表明,在肿瘤细胞、急性肺损伤和肠缺血再灌注损伤的上皮细胞中,STAT3通过增加半胱氨酸-谷氨酸双向转...
1. Saraiva, M. & O’Garra, A. The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 10, 170–181 (2010).2. Zhu, L. et al. IL-10 and IL-10 receptor mutations in very early onset inflammatory bowel disease. Gastroenterology Res. 10, 65–69 (2017).3. Glocker,...
1. Saraiva, M. & O’Garra, A. The regulation of IL-10 production by immune cells.Nat. Rev. Immunol.10, 170–181 (2010). 2. Zhu, L. et al. IL-10 and IL-10 receptor mutations in very early onset inflammatory bowel disease.Gastroen...
MCE 站:IL-10 Receptor 品牌:MedChemExpress (MCE) 概述:白细胞介素 10 受体 (IL-10R) 是一种 II 型细胞因子受体,由 2 个α 和 2 个β 亚基组成的四聚体。其中,α 亚基又称 IL-10RI,是一种配体结合亚基,而β 亚基又称 IL-10RII,是信号转导所需的辅助亚基。IL-10 受体表达主要在造血谱系细胞中...
2.Hu X, Chen J, Wang L, Ivashkiv LB (2007) Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J Leukoc Biol 82(2):237-43. Epub 2007 May 14. Review. 3.Cavalcante LB, Tanaka MH, Pires JR, et al...
6. Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A Interleukin-10 andthe interleukin-10 receptor. Annu Rev Immunol. 2001;19:683-765. 7. Takashi Tanikawa, Cailin Moira Wilke, Ilona Kryczek, Grace Y. Chen, JohnKao,Gabriel Nunez, and Weiping Zou.Interleukin-10 Ablation Promotes Tumor...
白细胞介素-10(interleukin-10,IL-10)是一种关键的抗炎细胞因子,由活化免疫细胞产生。虽然大多数造血细胞通过表达IL-10受体(IL-10 receptor,IL-10R)感受IL-10,但近期研究显示,巨噬细胞是抑制IL-10效应的主要靶细胞。IL-10位点的多态性带来了炎症性肠病(inflammatory bowel disease,IBD;包括溃疡性结肠炎和克隆恩...
（3）Hu X, Chen J, Wang L, Ivashkiv LB (2007) Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J Leukoc Biol 82(2):237-43. Epub 2007 May 14. Review.（4）Cavalcante LB, Tanaka MH, Pires JR, et al. (2012) Expression of the ...
IL-10 and IL-10 receptor defects in humans. Ann N Y Acad Sci 2011; 1246(1):102-7.Glocker EO, Kotlarz D, Klein C, Shah N, Grimbacher B. IL-10 and IL-10 receptor defects in humans. Ann N Y Acad Sci 2011;1246:102-7.
价格:元 规格: 10ug 50ug 联系方式:I47-825O-882O立刻购买 买家导航 IL10R细胞因子产品基本信息 产品名称: 重组人IL-10受体亚基α 产品又名: IL-10RA细胞因子, IL10R细胞因子 英文名称: Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a...