such as Crohn's disease and rheumatoid arthritis. Although IL-11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL-11, they sh...
such as Crohn's disease and rheumatoid arthritis. Although IL-11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL-11, they sh...
IL-11 and IL-6 activate signalling via assembly of the cell surface receptor gp130; however, it is unclear how signals are transmitted across the membrane to instruct cellular responses. Here we solve the cryoEM structure of the IL-11 receptor recog
which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternati...
Structure. 2007;15:441–8. Article CAS PubMed PubMed Central Google Scholar Thiem S, Pierce TP, Palmieri M, Putoczki TL, Buchert M, Preaudet A, et al. mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice. J Clin Invest. 2013;123:767–81. CAS PubMed ...
用途:Insulin, recombinant human (rHu) is identical in function and structure to the native human sequence. A hormone consisting of two polypeptide chains, rHu Insulin′s A-chain (21 amino acids) and B-chain (30 amino acids) are covalently linked by disulfide bonds between cysteine residues. ...
The articles contained within this special issue expound upon human studies examining epithelial gene expression, alterations in epithelial structure, as well as in vitro studies investigating epithelial function relevant to asthma. This special issue contains 3 original research articles and 4 review ...
Analysis of common problems in experimental operation by ELISA kit(1) Analysis of common problems in experimental operation by ELISA kit(2) Analysis of common problems in experimental operation by ELISA kit(3) Analysis of non-specific coloration in ELISA ...
The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement[J]. J Biol Chem, 2020,295(24):8285-8301. DOI: 10.1074/jbc.RA119.012351 . 返回引文位置Google Scholar 百度学术 万方数据 11 Balakrishnan L , Soman S , Patil YB ,et al. IL...
2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain (1). Recommended Applications WB, IHC, ICC, FC IL-11R alpha生产厂家 Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000