2024 年 8 月 6 日,清华大学生命科学学院/北京生物结构前沿研究中心王新泉教授课题组在《结构》(Structure)杂志在线发表研究论文,题目为「人源 IL-12 信号复合物的结构与组装」(Structure and assembly of the human IL-12 signaling complex)...
2024年8月6日,清华大学生命科学学院/北京生物结构前沿研究中心王新泉教授课题组在《结构》(Structure)杂志在线发表研究论文,题目为“人源IL-12信号复合物的结构与组装”(Structure and assembly of the human IL-12 signaling complex)。该研究成果增强了对IL-12信号起始的理解,同时也为IL-12的改造和治疗应用开辟了...
▲图1.IL-12家族细胞因子结合受体及其下游信号组分的结构模型 2024年8月6日,清华大学生命科学学院/北京生物结构前沿研究中心王新泉教授课题组在《结构》(Structure)杂志在线发表研究论文,题目为“人源IL-12信号复合物的结构与组装”(Struct...
结构式(Structure) 运输和保存方法 粉末-25~-15℃保存,有效期3年;溶于溶剂,-85~-65℃保存,有效期2年 注意事项 1. 为了您的安全和健康,请穿实验服并戴一次性手套操作。 2. 粉末溶解前请先短暂离心,以保证产品全在管底。 3. 避光干燥保存,避免反复冻融。
Specific topics discussed in this article include the structure, regulation, function, receptor utilization, and role of IL-12 related cytokines in respiratory disease.doi:10.1016/B0-12-370879-6/00482-8M.J. WalterWashington University School of Medicine, St Louis, MO, USAEncyclopedia of Respiratory...
https://www.cusabio.com/c-20630.html#:~:text=Interleukin%20is%20a%20kind%20of,a%20solid%20structure%20and%20function. https://mp.weixin.qq.com/s/_x83HGtWXqbW1tSZ-jULVQ Interleukins in cancer: from biology to therapy. Nat Rev Cancer. 2021 Jun 3 : 1–19. ...
Each IL-12 family member is composed of alpha-subunit with a helical structure similar to type 1 cytokines like IL-6 and a beta-subunit structurally related to the extracellular regions of Type 1 cytokine receptors (e.g. soluble IL-6 receptor). ...
Structure Heterodimer Distribution IL-12 is produced by monocytes, macrophages, neutrophils, dendritic cells and B cells. In the CNS, astrocytes and microglia are the main sources of IL-12. Function IL-12 is produced by myeloid cells and DCs in response to microbial stimuli, such as thos...
roleinthetUlTlOrintemalmedicinetreatment.5-FU,thestructure ofwhichissimilartouraciland thymine,is the cell-cyclespecific medicine.It mainly inhibitsthe S-phase cells’DNA synthesis.Inaddition itprevents theuracilandorotic acidfrom incorporating
BD Pharmingen APC Rat Anti-Mouse IL-12 (p40/p70) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.