前者产生IL-2 、IL-3 、IFN-γ和淋巴毒素及粒细胞-巨噬细胞集落刺激因子(granulocy te-macrophage colony stimulating factor ,GM-CSF)等, 参与细胞免疫;而后者则产生IL-4 、IL-5 、IL-10 和IL-13 等细胞因子,辅助B 细胞产生抗体,参与体液免疫。某些病原菌只能被Th1或Th2 有效地抑制。 IL-1 、IL-6 ...
macrophage colony-stimulating factor production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-17 production positive regulation of tumor necrosis factor production positive regulation of natural killer cell proliferation positive ...
Macrophage activator having IL-12 production inducing activityPROBLEM TO BE SOLVED: To provide a macrophage-activating agent, interleukin 12-production-inducing agent and immunostimulant. SOLUTION: This macrophage-activating agent, interleukin 12-production-inducing agent and immunostimulant contains an acidic...
前者产生IL-2 、IL-3 、IFN-γ和淋巴毒素及粒细胞-巨噬细胞集落刺激因子(granulocy te-macrophage colony stimulating factor ,GM-CSF)等, 参与细胞免疫;而后者则产生IL-4 、IL-5 、IL-10 和IL-13 等细胞因子,辅助B 细胞产生抗体,参与体液免疫。某些病原菌只能被Th1或Th2 有效地抑制。 IL-1 、IL-6 ...
IL-4 和 IL-13 在交替激活的巨噬细胞中诱导 c-Myc 表达(MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology.),相反,LPS 诱导的 HIF-1α 上调与 c-Myc 下调同时发生Myc 。总体而言,在没有二次刺激的情况下,训练...
Blockade of either PGE2 or NO production with indomethacin or l-NAME reversed promastigote inhibition of LPS induced IL-12 production. Promastigotes also increased macrophage arginase-1 expression and enhanced arginase activity, both of which were substantially reduced in TLR-4 but not TLR-2 ...
批量或定制请求 Application Created with Sketch. 图:1/32 IL-1 beta (Pro-form) Antibody (12-7114-82) in Flow In vitro-cultured mouse monocytes unstimulated (left) or stimulated with LPS (right), in the presence of Protein Transport Inhibitor Cocktail (Product # 00-4980-03),...
Tumor-associated macrophage and tumor-cell dually transfecting polyplexes for efficient interleukin-12 cancer gene therapy. Adv. Mater. 33, e2006189 (2021). PubMed Google Scholar Hewitt, S. L. et al. Intratumoral IL12 mRNA therapy promotes TH1 transformation of the tumor microenvironment. Clin....
11. ZHAO L, YE W, ZHU Y, et al. Distinct macrophage polarization in acute and chronic gout[J]. Lab Invest, 2022,102(10):1054-1063. 12. GRASSI F, MARINO R. The P2X7 receptor in mucosal adaptive immunity[J]...
Intratumoral administration of RdB/IL-12/IL-18 improved antitumor effects, as well as increased survival, in B16-F10 murine melanoma model. The ratio of T-helper type 1/2 cytokine as well as the levels of IL-12, IL-18, interferon-γ and granulocyte–macrophage colony-stimulating factor was...