Fortes MRS, Li Y, Collis E, Zhang Y, Hawken RJ. 2013. The IGF1 pathway genes and their association with age of puberty in cattle. Animal Genetics 44(1): 91-95.Fortes, M. R., Li, Y., Collis, E., Zhang, Y., & Hawken, R. J. (2013). The IGF1 pathway genes and their ...
Insulin-like growth factor-1 (IGF1) pathway plays a critical role in malignant transformation, and epidemiology studies have also shown that single nucleotide polymorphisms (SNPs) in IGF1 pathway genes are associated with prostate cancer risk. However, the clinical significance of these SNPs on pros...
大家好,今天给大家解读一篇题为 Mrcl* macro phage-derived lGFlmitigates crystalne phropathyby promo ting renal tubule cell prolifer ationvia the AKT/Rb signaling pathway(Mrcl*巨噬细胞衍生的lGFl通过AKT/Rb信号通路促进肾小管细胞增殖,减轻晶体肾病变)肾结石的形成非常普遍,发生率高达14.8%,在初次结石发作...
参考文献:Yan B, Zeng C, Chen Y, Huang M, Yao N, Zhang J, Yan B, Tang J, Wang L, Zhang Z. Mechanical Stress-Induced IGF-1 Facilitates col-I and col-III Synthesis via the IGF-1R/AKT/mTORC1 Signaling ...
参考文献:Yan B, Zeng C, Chen Y, Huang M, Yao N, Zhang J, Yan B, Tang J, Wang L, Zhang Z. Mechanical Stress-Induced IGF-1 Facilitates col-I and col-III Synthesis via the IGF-1R/AKT/mTORC1 Signaling Pathway. Stem Cells Int. 2021 Dec 6;2021:5553676. doi: 10.1155/2021/5553676...
Giambartolomei GH, Rivas MA, et al. Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ respo...
重庆医科大学硕士学位论文IGF-1信号通路在糖尿病脑病中的作用机制研究姓名:***请学位级别:硕士专业:老年医学指导教师:**萍201105重庆医科大学硕士研宄生学位论文IGF-I信号通路在糖尿病脑病中的作用机制研究摘要背景糖尿病对中枢神经系统(Centralnervoussystem,CNS)的影响近年来己引起人们的广泛重视,糖尿病脑病(Diabetic...
sites http://microrna.sanger.ac.uk /mirscan Tool for miRNA Functional Analysis Summary IGF-1 is a potent survival factor for vascular cells and stem cells, preventing oxLDL-induced mitochondrial dysfunction, cytochrome C release and apoptosis through a IGF-1R/PI3 – kinase/Akt signaling pathway....
通路(Pathway) Protein Tyrosine Kinase CAS号(CAS NO.) 867160-71-2 分子式(Formula) C26H23N5O 分子量(Molecular Weight) 421.51 纯度(Purity) ≥98% 溶解性(Solubility) 溶于DMSO 运输和保存方法 -25~-15℃保存,有效期3年 注意事项 1. 为了您的安全和健康,请穿实验服并戴一次性手套操作。
为了确定功能研究的候选机制和分子的优先顺序,研究人员将来自中年多能祖细胞的单细胞RNA-SEQ数据输入到Invenuity Pathway Analysis中。上游调节因子分析预测在中年骨髓微环境中IGF2升高,NRG1、IGF1、TGF-β1和EGF降低。使用中年LT-HSC RNA-SEQ数据证实了这些预测。