Insulin/IGF-1 signaling pathway driving ag- ing and cancer as a target for pharmacological intervention. Exp Gerontol 2003; 38: 1041-1049Anisimov VN. Insulin/IGF-1 signaling pathway driving aging and cancer as a target for pharmacological intervention. Exp Gerontol. 2003;38:1041-9....
英文名称:Insulin/IGF-1 Signaling Pathway Antibody Sampler Kit 包装信息:1Kit 备注: 见优宁维官网 赛信通(上海)生物试剂有限公司 联系电话: 21-80243558 86218024 产品介绍: 英文名称:Insulin/IGF-1 Signaling Pathway Antibody Sampler Kit 基本信息 中文名称 Insulin/IGF-1 Signaling Pathway Antibody Sampler...
Insulin and IGF-1 act on two closely related tyrosine kinase receptors to initiate a cascade of signaling events. These signaling events activate a variety of biological molecules, including kinases and transcription factors, which regulate cell growth, survival and metabolism.Type I insulin-like growt...
Insulin/IGF-1 Signaling Pathway Antibody Sampler Kit(1)结合特异性抗原:抗体与其他免疫球蛋白分子区别,就在于抗体能与相应抗原发生特异性结合,在体内导致生理或病理效应;在体外产生各种直接或间接的可见的抗原抗体结合反应。抗体是靠其分子上的特殊的结合部位与抗原结合的。 (2)激活补体:抗体与相应抗原结合后,借助暴...
Insulin/IGF-1 Signaling Pathway Antibody Sampler Kit 价 格 电议 起批量 ≥1 Kit 最小起订电询 供货总量电询 发货地址上海市浦东新区 建议售价￥电议/Kit 更新日期 2025年05月18日 产品规格见优宁维官网 即时洽谈 立即询价 查看联系方式 收藏产品 发送留言 举报 VIP4年 上海优宁维生物科技股份有限...
Integration of the insulin/IGF-1 (Ins/IGF-1) signaling pathway and the second messenger ROS-mediated redox signaling pathways involve regulatory cross-talk processes between these pathways. The molecular mechanisms of signaling via cross-talk may play an important role in the mechanisms of regulation...
melanogaster has a homologous insulin/IGF-1-like pathway consists of insulin receptors, including mammalian insulin receptor substrates (IRS) and kinase homologs, and a forkhead transcription factor. These insulin receptors reduce signalling stress resistance and extend the longevity14. Senescence represents...
El-Ami T, Moll L, Carvalhal Marques F, Volovik Y, Reuveni H, Cohen E (2014) A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity. Aging Cell 13: 165 - 174El-Ami T, Moll L, Carvalhal Marques F, Volovik Y, Reuveni H...
The production of IGF-1 is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signaling pathway post GH receptor including SHP2 and STAT5B. Recombinant human IGF-1 are globular ...
The target of rapamycin (TOR) signaling pathway induces the development of oxidative stress resistance (Sugawara et al., 2019), whereas oxidative and heat stress tolerance is associated with the Ins/IGF-1 pathway (Furuhashi & Sakamoto, 2016). In the Ins/IGF-1 signaling pathway, daf-16 is ...