Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am J Physiol Endocrinol Metab. 2003;285:E1064-E1071.Barbieri M, Bonafe M, Franceschi C, Paolisso G. Insulin/ IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from...
Insulin/IGF-1 Signaling Pathway Antibody Sampler Kit(1)结合特异性抗原:抗体与其他免疫球蛋白分子区别,就在于抗体能与相应抗原发生特异性结合,在体内导致生理或病理效应;在体外产生各种直接或间接的可见的抗原抗体结合反应。抗体是靠其分子上的特殊的结合部位与抗原结合的。
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1) insulin/IGF signal pathway 胰岛素/类胰岛素途径2) Insulin Pathway 胰岛素途径3) insulin-mimetic 类胰岛素 1. This review focuses on the signaling pathways mediating the insulin-mimetic and anticancer effects of vanadium compounds, as well as the correlationship between them. 本文对近年来关于钒...
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Insulin-like Growth Factors and Receptors: IGF1R, IGF2, IGFBP1.SH3/SH2 Adaptor Protein: CBL, GAB1, GRB2, IRS4, NCK1.Other Genes Associated with Insulin Receptor Proteins: CAP1, DOK1, DOK2, DOK3, FRS2, FRS3, INSR, PDPK1, PPP1CA, PTPN1, PTPRF, SHC1. PI-3Kinase Pathway: Comp...
Despite the strong association of the insulin/insulin-like growth factor (IGF) signaling (IIS) pathway with tumor initiation, recurrence, and metastasis, the mechanism by which this pathway regulates cancer progression is not well understood. Here, we report that IIS supports breast cancer stem cel...
1. Insulin/insulin-like growth factor signaling and pancreatic beta cell apoptosis; 胰岛素/胰岛素样生长因子信号转导通路与胰岛β细胞凋亡2) IGF-1 receptor signaling 类胰岛素样生长因子受体信号转导3) Insulin like growth factor-1 receptor-NOS-NO signaling 胰岛素样生长因子-1受体-NOS-NO信号通路...
Insulin,IGF-1andGLP-1signalinginneurodegenerativedisorders:Targetsfordiseasemodification?FaresBassila,b,Pierre-OlivierFernaguta,b,ErwanBezarda,b,c,WassiliosG.Meissnera,b,c,*aUniv.deBordeaux,InstitutdesMaladiesNeurode´ge´ne´ratives,UMR5293,Bordeaux,FrancebCNRS,InstitutdesMaladiesNeurode´ge´ne...
An accumulating body of evidence suggests the involvement of an evolutionary conserved insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS) pathway in the regulation of the life and health span in nematodes, flies, rodents, and humans. We studied the association between insulin/IGF-1 si...