Fortes MR, Li Y, Collis E, Zhang Y, Hawken RJ: The IGF1 pathway genes and their association with age of puberty in cattle. Anim Genet 2013, 44 (1) : 91–95.Fortes MR , Li Y , Collis E , Zhang Y & Hawken RJ . ( 2013a ) The IGF1 pathway genes and their association with ...
大家好,今天给大家解读一篇题为 Mrcl* macro phage-derived lGFl mitigates crystalne phropathy by promo ting renal tubule cell prolifer ationvia the AKT/Rb signaling pathway(Mrcl*巨噬细胞衍生的lGFl通过AKT/Rb信号通路促进肾小管细胞增殖,减轻晶体肾病变)肾结石的形成非常普遍,发生率高达14.8%,在初次结石...
大家好,今天给大家解读一篇题为 Mrcl* macro phage-derived lGFlmitigates crystalne phropathyby promo ting renal tubule cell prolifer ationvia the AKT/Rb signaling pathway(Mrcl*巨噬细胞衍生的lGFl通过AKT/Rb信号通路促进肾小管细胞增殖,减轻晶体肾病变)肾结石的形成非常普遍,发生率高达14.8%,在初次结石发作...
The regulatory mechanisms of IGF1 in the osteogenic differentiation of canine MSMSCs via BMP2⁃Smad1/5 signaling pathway LIAO Chunhui1, LI Mingfei2, YE Jinmei1, PENG Wei2, CHEN Songling2. 1. Department of Or⁃ thodontics, Guangzhou Women and Children′s Medical Center, Guangzhou 510000...
Insulin-like growth factor-1 (IGF1) pathway plays a critical role in malignant transformation, and epidemiology studies have also shown that single nucleotide polymorphisms (SNPs) in IGF1 pathway genes are associated with prostate cancer risk. However, the clinical significance of these SNPs on pros...
大家好,今天给大家解读一篇题为Mrcl* macro phage-derived lGFl mitigates crystalne phropathy by promo ting renal tubule cell prolifer ationvia the AKT/Rb signaling pathway(Mrcl*巨噬细胞衍生的lGFl通过AKT/Rb信号通路促进肾小管细胞增殖,减轻晶体肾病变)肾结石的形成非常普遍,发生率高达14.8%,在初次结石发...
为了确定功能研究的候选机制和分子的优先顺序,研究人员将来自中年多能祖细胞的单细胞RNA-SEQ数据输入到Invenuity Pathway Analysis中。上游调节因子分析预测在中年骨髓微环境中IGF2升高,NRG1、IGF1、TGF-β1和EGF降低。使用中年LT-HSC RNA-SEQ数据证实了这些预测。
(Supplementary Data1). IL-6 activity has been shown to regulate downstream JAK/STATs45and to crosstalk with insulin/IGF143. The type II diabetes pathway was also identified as enriched in the EPI; this includes genes encoding insulin and IGF receptors as well as downstream PI3K signalling ...
Expression Analysis of IGF1-PI3K-Akt-Dependent Pathway Genes in Skeletal Muscle and Liver Tissue of Yellow Feather Broilers SHU JingTing1( ),JI GaiGe1,SHAN YanJu1,ZHANG Ming1,JU XiaoJun1,LIU YiFan1,TU YunJie1,SHENG ZhongWei1,TANG YanFei2,JIANG HuaLian2,ZOU JianMin1( ...
通路(Pathway)分析结果显示,差异表达基因编码的蛋白共富集61条细胞信号通路,其中包括IGFl信号通路。采用Western Blot检测IGF1信号通路相关分子,发现ET组IGF1,ERK及CREB表达上调。结论:4周有氧跑台训练引起抑郁症SD大鼠海马组织全基因表达谱发生变化,可能通过调控IGF1信号通路相关分子促进机体记忆学习能力的提高。