Solution studies provide a basis for elucidating the catalytic mechanism of ATP hydrolysis and actin activation. Measurement under steady-state conditions reveal a correlation between the velocity of shortening of different muscle types and the ATPase rate of the actomyosin extracted from them (e.g. ...
The chemical mechanism of ATP hydrolysis by nitrogenase is discussed in terms of results from isotopic exchange studies using [18O4]-Pi, b,g-[18O]-ATP, and g-[18O4]-ATP as probes of reversibility (ATP = ADP + Pi) and of the freedom of rotation around the O-Pb bond in enzyme-...
Hydrolysis of ATP by F1 can be described only on the basis of a dual-site mechanism 来自 Elsevier 喜欢 0 阅读量: 20 作者:JA Berden,AF Hartog,CM Edel 摘要: Biochim Biophys Acta. 1991 Mar 29;1057(2):151-6. Research Support, Non-U.S. Gov't; Review 关键词:...
Describe the mechanism of ATP synthesis. What are the complex equilibria involved in ATP hydrolysis? ATP can be used to drive reactions that would otherwise be energetically unfavorable. How does ATP do this? How does ATP actually power reactions?
In Boyer's hypothesis (2), tight binding of ADP and phosphate leads to formation of ATP; energy of the proton gradient is necessary for ATP release. Binding of ADP and phosphate to a second site accelerates this process ("dual site" mechanism)....
Rate acceleration of ATP hydrolysis by F1Fo-ATP synthase The rate acceleration of ATP hydrolysis by F1Fo-ATP synthase is of the order of 10(11)-fold. We present a cyclic enzyme mechanism for the reaction, relate ... AE Senior,S Nadanaciva,J Weber - 《Journal of Experimental Biology》 ...
Thus, our data show that RecQ translocates on ssDNA by efficiently coupling the hydrolysis of one ATP molecule into structural alterations that result in movement of approximately two nucleotides, presumably by an inchworm mechanism. These attributes are consistent with the function of RecQ in ...
Despite the potential to promote catalysis by utilizing the significant binding energy available through their interaction with substrate, ATP hydrolysis is frequently a part of the mechanism of these enzymes. The reasons for this have become clearer in recent years, and a surprising range of ways ...
atphydrolysis天文学水解phosphateastronomy ATPHydrolysis Presentedby:RamiAmro Instructor:Dr.Neiman • Ch.13:Directmovementofthemotorsalongthe filamentthoughttobearesultofconformational changeswhileitisattached. • Ch.14: • Howchangesinnucleotidestatemodifythe associationofamotorwiththefilament. • Howthese...
The DNA Gyrase-Quinolone Complex ATP HYDROLYSIS AND THE MECHANISM OF DNA CLEAVAGE 来自 掌桥科研 喜欢 0 阅读量: 38 作者:SC Kampranis,A Maxwell 摘要: Quinolone binding to the gyrase-DNA complex induces a conformational change that results in the blocking of supercoiling. Under these conditions ...