New Perspective on the Reversibility of ATP Synthesis and Hydrolysis by Fo·F1-ATP Synthase (Hydrolase)Fo·F1-ATPasereversibility of enzymatic catalysisF o ·F 1 -ATPases of mitochondria, chloroplasts, and microorganisms catalyze transformation of proton motive force (the difference between the ...
A Possible Mechanism for ATP Synthesis and ATP Hydrolysis by the FOF1 ATPase of ChloroplastsOn FOF1 ATPases, three catalytic nucleotide sites with different properties were found. Following hypotheses for ATP synthesis (1,2) these properties change for each site in an alternating or a cyclic ...
Weber J and Senior AE. ATP synthase: what we know about ATP hydrolysis and what we do not know about ATP synthesis. Biochim Biophys Acta 1458: 300-309, 2000.J. Weber, A.E. Senior, ATP synthase: what we know about ATP hydrolysis and what we do not know about ATP synthesis, Biochim...
Bennun A.; "Hypothesis for coupling energy transduction with ATP synthesis or ATP hydrolysis", Nat New Biol. 1; 233(35):5-8 (1971)A. Bennun, "Hypothesis for Coupling Energy Transduc- tion with ATP Synthesis or ATP Hydrolysis," Nature New Biology, Vol. 233, No. 35, 1971, pp. 5-8...
Because ATP synthesis and hydrolysis are reversible processes for CF1FO, our tentoxin-bound and reduced CF1FO structure is to our knowledge very likely the first visualization of the entry step of the ADP molecule for the subsequent ATP synthesis. γ-ε central shaft and the redox switch The...
hydrolysis reactionuniversal energy currencyChemical aspects of ATP and the phosphoanhydride bondsHistorical perspective on ATP synthesisQuantitative formulation of proton motive forceNomenclature and cellular location of ATP synthaseStructure of ATP synthaseThe mechanism of chemiosmotic coupling...
Enzyme activity is tightly coupled to rotation of γ, ε and the subunit III-ring, while ATP synthesis and hydrolysis are restricted to three of the six nucleotide binding sites located at each α/β interface. A special feature of higher plant CF1 is an additional regulatory domain in the ...
and results in the synthesis/hydrolysis of ATP. It is not the synthesis of ATP but its release from the synthase that is driven by the protonmotive force. Subunitsγandɛrotate relative to theα3β3hexamer to alter the nucleotide affinities (and hence binding) in theβ-catalytic sites. ...
A. (1997) Control of energy fluxes by the sarcoplasmic reticulum Ca 2+ -ATPase: ATP hydrolysis, ATP synthesis and heat production. FEBS Lett. 406: 201-204.de Meis L, Bianconi ML, Suzano VA (1997) Control of energy fluxes by the sarcoplasmic reticulum Ca 2+ -ATPase: ATP hydrolysis, ...
Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic co...