9. Sun Y, Li D, Ni C, Ge Y, Qian H, Ouyang Q, et al.ATP hydrolysis kinetics and thermodynamics as determinants of calcium oscillation in pancreatic β cells.Phys Rev Research2022, 4(4). 10. Wilson DF, Cember ...
Panaretou B , Prodromou C , Roe SM , O'Brien R , Ladbury JE , Piper PW & Pearl LH ( 1998 ) ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo . Embo J 17 : 4829 – 4836 ....
'In bacteriophage T4, a clamp loading pathway that utilizes the T4 clamp loader (gp44/62) and ATP hydrolysis initially to form a complex with the clamp (gp45) has been demonstrated, followed by interaction with DNA and closing of the clamp. However, the recent observation that gp45 exists...
Analysis of Walker motif B mutants suggests that ATP hydrolysis at the two ABC domains is strictly coordinated and is essential for the function of Uup in vivo. 展开 关键词: Hydrolysis Essential Function ATPbinding Cassette Excision Transposons ...
(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites ...
multisubunitproteincomplexeswhichfunctioninATPhydrolysisandprotontransport.V-ATPasesarefoundintheendomembranesystemofeukaryoticorganisms,theplasmamembraneofprokaryotes,andtheplasmamembrane25ofspecializedcellsinhighereukaryotes.Inyeast,forexample,theenzymecomplexiscomposedoftwostructuralandfunctionaldomains,whichinclude14...
Moreno-Sanchez R,Espinosa-Garcia MT,Raja JC.Con-trol of respiration and ATP hydrolysis in uncoupled mito-chondria.Integration of michon-drial function. 1988Moreno Sanchez R.Control of respiration and ATP hydrolysis in uncoupled mitochondria[A].1988....
followed by ATP synthesis and ATP release. This concept recognizes that theβ-subunit can exist in three conformations: open, tight, or loose forms. These forms correspond to the binding, synthesis, and release of ATP and are driven by the rotation of theγ-subunit. The hydrolysis of ATP wi...
ATP binding and hydrolysis were found to be essential for the function of Hsp90 (12, 13), and competitive inhibitors for ATP binding like geldanamycin were shown to be potent antiproliferative agents (14, 15). The first indications that Hsp90 conformation is influenced by ATP were reported by...
Heteroduplex DNA and ATP induced conformational changes of a MutS mismatch repair protein from Thermus aquaticus. ATP hydrolysis by MutS homologues is required for the function of these proteins in mismatch repair. However, the function of ATP hydrolysis in the repair ... BISWAS, Indranil,VIJAYVAR...