Huntingtin-associated protein 1 (HAP1), the first identified HTT-binding partner, is highly expressed in the central nervous system, and has been found to associated with neurological diseases. Mounting evidence suggests that HAP1 functions as a component of cargo-motor molecules t...
[translate] aLive album <<1 2个世纪Concert>>活册页 [translate] aDESIGNATION: 正在翻译,请等待... [translate] aHuntingtin-Associated Protein 1 is essential for postnatal growth by regulating neurogenesis Huntingtin伴生的蛋白质1为出生后成长是根本的通过调控neurogenesis [translate] ...
Huntingtin‐associated protein‐1 is a synapsin I‐binding protein regulating synaptic vesicle exocytosis and synapsin I traffic Accepted ArticleThis article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading ...
Since then, a growing body of evidence has suggested that huntingtin has a major function in the control of axonal transport and that this function requires the HAP1 protein. Indeed, HAP1 binds not only to the p150Glued subunit of dynactin but also to the kinesin light chain 2, ...
目的拟探讨亨廷顿蛋白相关蛋白1(HAP1)与脑源性神经营养因子(BDNF)及其受体p75NTR的胞吞和逆向囊泡运输关系,深入阐述亨廷顿舞蹈病的分子生物学机制。 更多例句>> 3) Huntingtin-associated protein (HAP) 亨廷顿蛋白相关蛋白 例句>> 4) huntingtin 亨廷顿蛋白 ...
Using the yeast two-hybrid system, we isolated a rat cDNA encoding part of a protein that interacts with HAP1, and we confirmed the specificity of this interaction using an in vitro protein-binding assay. We called the protein Duo because it is closely related to the human protein Trio but...
The hypothalamus responds to circulating leptin and insulin in the control of food intake and body weight. A number of neurotransmitters in the hypothalamus, including γ-aminobutyric acid (GABA), also have key roles in feeding. Huntingtin-associated protein 1 (Hap1) is expressed more abundantly ...
Huntingtin-associated protein 1 (HAP1), the first protein identified to bind to huntingtin (HTT) (Li et al. 1995), native HAP1 in the brain was diffusely distributed in the neurons (Li et al. 1998) and considered a clathrin and alpha-adaptin-binding protein (Waelter et al. 2001). ...
中文名称:huntingtin-associated protein 1 中文同义词: 英文名称:huntingtin-associated protein 1 英文同义词:huntingtin-associated protein 1;Anti-Hap1 (C-terminal) antibody produced in goat;RP23-392I3.11, HAP-1, MGC31449 CAS号: 分子式: 分子量:0 ...
Huntington's disease is caused by an increased Cytosine Adenine Gaunine (CAG) repeat number in a gene coding for a protein called huntington. The trinucleotide CAG codes for the amino acid glutamine and the expanded CAG repeat is translated into an unbroken glutamine stretch. The d...