Human primary monocyte-derived macrophages (MDM)In addition to CD4doi:10.1007/978-1-0716-1871-4_9Francesca.GrazianoTranslational Sciences, Sanofi, Chilly-Mazarin, France.Elisa.VicenziViral Pathogenesis and Biosafety Group, San Raffaele Scientific Institute, Milan, Italy.Guido.Poli...
MDMMonocyte Derived Macrophages MDMMoi Dix Mois(band) MDMMid-Day Meal(India) MDMMelodic Death Metal(music genre) MDMModern Digital Militia(band) MDMMultiplexer/Demultiplexer MDMMix Design Methods(Langhorne, PA) MDMMarket Development Manager MDMModern Drunkard Magazine(est. 1996) ...
human macrophageslipoprotein lipaseHuman monocytes isolated from either defibrinated blood or buffy coat were shown to produce and secrete lipoprotein lipase during culture. The secretion occurred constitutively. Low levels of enzyme activity in the medium from freshly isolated cells increased with time ...
macrophagesinfectionmonocyte‐derived macrophagesalmonellaIn the gastrointestinal tract, the tug of war for iron may provide a new way to vaccinate. Recent work shows that immunizing mice with siderophores (small molecules that microbes produce to capture iron) foils pathogen colonization and may instead...
Infection of human monocyte-derived macrophages in vitro with virulent Shigella flexneri resulted in cell death which involved rupture of the plasma membrane, cell swelling, disintegration of ultrastructure, and generalized karyolysis. These features bore resemblance to oncosis and are in striking contras...
We have investigated poly(ADP-ribosyl)ation processes in human monocyte-derived macrophages and the effect of the activating cytokine, interferon γ (IFN-γ) on these processes. IFN-γ was shown to increase the activity of poly(ADP-ribose) polymerase in human macrophages. A 2–3-fold enhancemen...
Conflicting reports relating to phagolysosomal pH in CF macrophages have been published, in part related to the use of pH-sensitive fluorescent probes where potential inadequacies in experimental design can be a contributing factor (e.g. employing probes with incorrect pKa for the cellular compartment...
Matrix metalloproteinase-12 gene regulation by a PPAR alpha agonist in human monocyte-derived macrophages[J].Experimental Cell Research,2008,(18):3405-3414.doi:10.1016/j.yexcr.2008.09.002.Souissi IJ, Billiet L, Cuaz-Perolin C, Slimane MN, Rouis M (2008) Matrix metalloproteinase-12 gene ...
Human monocyte-derived macrophages in culture produced lipoprotein lipase. Although freshly isolated blood monocytes did not secrete much lipase activity, 1 d in culture was sufficient to trigger measureable enzyme production. During 3 wk in culture, maximal activity was attained after 7 d. At all ...
Human monocyte-derived macrophages in culture were shown to synthesize and secrete a lipid transfer protein. The human monocyte-derived macrophage transfer protein showed the following characteristics: (i) linear secretion rate over a 24-h period, which was blocked completely by cycloheximide and stimul...