Human induced pluripotent stem cells (iPSCs) have emerged as an invaluable resource for basic research, disease modeling, and drug discovery over recent years. Given the numerous advantages of iPSCs over alternative models—including their human origin, their ability to be differentiated into almost ...
Recently, human somatic cells have been reprogrammed directly to pluripotency by ectopic expression of four transcription factors (Oct4, Sox2, Klf4 and Myc) to yield induced pluripotent stem (iPS) cells. Human iPS cells are a potential source of patient-specific pluripotent stem cells that would b...
Human pluripotent stem-cell-derived islets (hPSC-islets) are a promising cell resource for diabetes treatment1,2. However, this therapeutic strategy has not been systematically assessed in large animal models physiologically similar to humans, such as non-human primates3. In this study, we generated...
Finally,pluripotent stem cells are amenable to genetic labeling and can thus be used for dissecting basic biology,and for creating disease models and screening systems.Successful gene delivery(however)depends on easy cloning systems to rapidly generate vectors,gene delivery methods to deliver these vecto...
Despite their rapidly-expanding therapeutic potential, human pluripotent stem cell (hPSC)-derived cell therapies continue to have serious safety risks. Transplantation of hPSC-derived cell populations into preclinical models has generated teratomas (tumors arising from undifferentiated hPSCs), unwanted tissues...
Human Pluripotent Stem Cell Cryopreservation Medium人多能干细胞冻存液 价格￥1740 起批量≥1瓶 最小起订1瓶 供货总量80瓶 发货地址广东省深圳市 建议售价￥电议 更新日期2025年02月25日 产品规格50 ml 即时洽谈立即询价查看联系方式 收藏产品发送留言 ...
Human Pluripotent Stem Cell Naïve State qPCR Array, Type 5 (Catalog #07525) hPSC Naïve State qPCR Array, 1 x 384-well plate plate TBP qPCR Control Template, 1 vial Products for Your Protocol To see all required products for your protocol, please consult theProtocols and Documentation. ...
RSeT human ES cells showed similarity to the pluripotent population, inducible GATA6-SOX17 cells were similar to blastoid-derived hypoblast, and inducible GATA3-AP2γ cells showed similarity to post-implantation-like trophoblast stem cells, but not to blastoid-derived trophectoderm-like cells (Exten...
Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development | Physiological Reviews 以下为全文翻译(水平有限,仅供参考): 摘要: 体细胞核移植的发现证明,体细胞可以携带与受精卵相同的遗传密码,激活该密码的部分足以将细胞重新编程到早期发育状态。近半个世纪后,诱导多能干细胞 (iPSC...
This lead to the derivation of embryonic stem (ES) cells that have proved to be superior to EC cells as research tools. With the recognition that EC and ES cells shared properties with cells of the early embryo and germ cells, attempts were made to obtain pluripotent stem cells directly ...