Biomedical and Behavioral ResearchGenetics and ReproductionCaroline Chisholm Centre for Health Ethics, East Melbourne, Australia.doi:10.1007/BF03351445Norman FordSpringer International PublishingMonash Bioethics ReviewFord, N. (2006). "Human pluripotent stem cell research and ethics." Monash Bioeth Rev 25(...
ethicsresearchstakeholdertranslational medicineExperimental therapies with embryonic stem cells (hESCs) and, more recently, human induced pluripotent stem cells (hiPSCs) are steadily gaining ground in clinical practice. The implementation of such novel high-risk/high-potential treatments calls for proper ...
Human induced pluripotent stem cells (iPSCs) were obtained from the Cell Bank of the Chinese Academy of Sciences (Shanghai, China). The iPSC line (DYR0100, catalog no. SCSP-1301) underwent rigorous validation for pluripotency and were confirmed to be free of mycoplasma contamination. Cultures ...
Human induced pluripotent stem cells (hiPSCs) can be endlessly produced and efficiently differentiated into cardiomyocytes (hiPSC-CMs) enabling development of human-based cell models for the research of cardiac diseases and therapies6. However, hiPSC-CMs are developmentally immature and structurally, funct...
Pancreatic β cells differentiated from stem cells provide promise for cell replacement therapy of diabetes. Human pluripotent stem cells could be differentiated into definitive endoderm, followed by pancreatic progenitors, and then subjected to endocrinal differentiation and maturation in a stepwise fashion...
induced pluripotent stem cells; neurospheres; 3D culture; neurite outgrowth; neurotoxicity Graphical Abstract1. Introduction Environmental stressors, such as chemicals or the medical drugs could have a toxic effect on humans which may occur at any stage of their life, during fetal development, ...
Background: The aim of this study was to test the feasibility and safety of subretinal transplantation of human induced pluripotent stem cell (hiPSC)-derived retinal pigment epithelium (RPE) cells into the healthy margins and within areas of degenerative retina in a swine model of geographic atroph...
6.1Human embryonic stem cells Humanembryonic stem cells(hESCs) are isolated from theinner cell massof pre-implantationblastocystsand are pluripotent,i.e.have the ability to differentiate into any cell type of the body, bringing great potential to model human development and diseases as well as a ...
Human dental pulp pluripotent-like stem cells promote wound healing and muscle regeneration Article Open access 27 July 2017 Mesenchymal stem cells: amazing remedies for bone and cartilage defects Article Open access 23 November 2020 Introduction Duchenne muscular dystrophy (DMD) is an X-linked ...
In this report we describe a human pluripotent stem cell-derived vascular progenitor (MesoT) cell of the mesothelium lineage. MesoT cells are multipotent and generate smooth muscle cells, endothelial cells, and pericytes and self-assemble into vessel-like networks in vitro. MesoT cells transplante...