H. (2013) Blue light- induced dimerization of a bacterial LOV-HTH DNA-binding protein. Biochemistry 52, 6653- 6661Zoltowski, B.D.; Motta-Mena, L.B.; Gardner, K.H. Blue light-induced dimerization of a bacterial LOV-HTH DNA-binding protein. Biochemistry 2013, 52, 6653-6661....
human Limkain b1 protein [11] that contain additional RNA-binding RRM domains. Likewise, some bacterial proteins contain further fusions to the S1/Cold-shock-type OB fold RNA-binding domain (Fig.1; Additional file1). Sequence profile analysis and structural comparisons of the crystal structure of...
All suggests that the α2HTH module once separated from the whole protein conserves a compact conformation, integral to specific dimerization and DNA recognition. The module may thus be used for the search of drugs efficient in hindering topoisomerase II dimerization or binding to DNA.Anne Morant-...
Bacillus subtilis GabR, a Protein with DNA-binding and Aminotransferase Domains, is a PLP-dependent Transcriptional Regulator Bacillus subtilis GabR is a member of a poorly characterized but widespread family of chimeric bacterial proteins that have apparent DNA binding and aminot... BR Belitsky - 《...
The peptides comprise an EF-hand Ca-binding motif and portions of a HTH DNA-binding motif. The Eu(III)−peptide complexes catalyze hydrolysis of phosphate esters and supercoiled DNA.关键词:lithium alkali-metals phosphanides crystal structures ...
However, as the salivary gland invaginates, Scr mRNA and protein disappear. Homeotic genes, such as Scr, specify tissue identity by regulating the expression of downstream target genes. For many homeotic proteins, target gene specificity is achieved by cooperatively binding DNA with cofactors. ...
satellite DNAcentromeresyncytiumIn drosophila, the preblastodermic syncytial nuclear divisions occur very fast. In this short period of time chromosomes must condense, segregate and decondense, in conditions governed by maternally provided RNAs and proteins. In this report, we show that the Homo...
Description1-252aa, full length protein. MW: 28,261 Da. Purity >85% (SDS-PAGE) Size0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Baculovirus), 0.5 mg (E-Coli), 0.2 mg (Yeast) Concentrationn/a Applicationsn/a Other Names[putative DNA-binding transcriptional regulator; Uncharacterized...
To regulate their target genes, the Hox proteins of Drosophila often bind to DNA as heterodimers with the homeodomain protein Extradenticle (EXD). For EXD ... HD Ryoo,T Marty,F Casares,... - 《Development》 被引量: 339发表: 1999年 Control of antennal versus leg development in Drosophila....
Co-factor homeodomain proteins such as HTH and EXD canincrease the DNA-binding specificity of Hox protein transcription factors. HTH binds to the homeotic co-factor extradenticle (EXD) and translocates it to the nucleus. The co-expression of EXD and HTH with distal-less is required to ...