Structural classification of HTH DNA-binding domains and protein-DNA interaction modes - Wintjens, Rooman - 1996 () Citation Context ...lowed by an a-helix–turn–a-helix (H–HTH2) motif at their N-terminal ends. This kind of three helix structure has been previously reported to be ...
Domain characterization of Bacillus subtilis GabR, a pyridoxal 5′-phosphate-dependent transcriptional regulator Bacillus subtilis GabR is a transcriptional regulator consisting of a helix–turn–helix N-terminal DNA-binding domain, a pyridoxal 5'-phosphate (PLP)-bind... O Keita,I Tomokazu,G Masaru,...
These results show our chimeric peptide combines the characteristics of the parent motifs, maintaining both metal binding and DNA affinity. 展开 关键词: Calcium-binding peptide EF-hand HTH motif Lanthanide Homeodomain DOI: 10.1007/s007750000188 被引量: 43 ...
DNA binding properties of the purified Antennapedia homeodomain Proc. Natl. Acad. Sci. USA, 87 (1990), pp. 4093-4097 CrossrefView in ScopusGoogle Scholar 4 D.J Andrew The Sex combs reduced gene of Drosophila melanogaster has multiple transcripts Gene, 152 (1995), pp. 149-155 View PDFView...
B. subtilis GabR is the prototype for a family of bacterial transcriptional regulators that consist of an N-terminal HTH DNA-binding domain and a C-terminal domain containing PLP which, in GabR, forms an aldimine with the activating ligand. An overlay of GabR (orange) with the closed (gold...
The PoxCbh-binding DNA sequence in the promoter region of the cellobiohydrolase 1 gene cbh1 was identified. These results expand our understanding of the diverse roles of centromere protein B-like protein, the regulatory network of cellulase and xylanase gene expression, and regulatory mechanisms in...
The C protein binds DNA with a very high affinity using a carboxyl-terminal helix turn helix (HTH) motif which has similarity with the HTH from paired domain of Drosophila prd protein. Previous studies established that the protein is dimeric in free and DNA bound forms. We describe now the ...
In other eukaryotic chromatin proteins, this predicted DNA-binding domain is fused to a region with three conserved motifs that are also found in diverse eukaryotic chromatin proteins, such as the animal BAZ/WAL proteins, plant HB1 and MBD9, yeast Itc1p and Ioc3, RSF1, CECR2 and NURF1. ...
Uniquely, the HTH domain could also bind RNA. Atomic force microscopy revealed that binding of Rv0890c to DNA was sequence independent, and binding of adenine nucleotides to the protein induced the formation of higher order structures that may represent biocrystalline nucleoids. This represents the...