HSV-tk gene therapy for human renal cell carcinoma in nude mice. Cancer Gene Ther 2001;8:529-36.Pulkkanen KJ,Parkkinen JJ,Laukkanen,et al.HSV-TK gene therapy for human renal cell carcinoma in nude mice. Cancer Gene Therapy . 2001
transducted into human bladder cancer cell T24. HSV-TK gene transfection with GCV can effectively inhibit growth of human bladder cancer cell T24. The results suggest that therapy of HSV-TK gene will be a potential possibility of treatment of human bladder cancer. Key words:HSV-TK gene;gene ...
1) HSV-TK gene HSV-TK基因 1. Lung carcinoma targeted expression ofHSV-TK genecontrolled by radioinducible synchronizing positive feedback genetic circuit; 放射诱导HSV-TK基因在肺癌细胞中靶向、高效性表达的研究 2. MethodsHuman Tenon s capsule fibroblasts transferred by HSV-tk gene(HTFs-tk) and norm...
6) herpes simplex virus-thymidine kinase gene 单纯疱疹病毒-胸苷激酶基因补充资料:2型单纯疱疹病毒 2型单纯疱疹病毒 单纯疱疹病毒2型主要感染生殖道。HSV 2是最早被认为在宫颈癌病因中起重要作用的一种病毒。有学者发现宫颈癌患者中HSV 2抗体阳性率高达80%以上,而对照组仅为14.14%～57.14%,其抗原阳性率也远较...
单纯疱疹病毒胸苷激酶(HSV-tk)基因是肿瘤基因治疗研究中常用的自杀基因。其作用原理,是因为某些特定的酶蛋白基因如HSV … baike.baidu.com|基于140个网页 2. 单纯疱疹病毒胸苷激酶基因 单纯疱疹病毒胸苷激酶基因(HSV-TK)/丙氧鸟苷(GCV)系统4) Deoxyguanosine 脱氧鸟苷 更多例句>> 5) HSV-TK/GCV 单纯疱疹 … ...
Cancer-specific targeting of an adenovirusdelivered herpes simplex virus thymidine kinase suicide gene using translational control[J]. J Gene Med ,2006, 8: 1105–1120. [2] N Pedersen, MW Pedersen, MS Lan. The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small...
Effect of Regulation of HSV-tk Gene Expression and Tumor Killed Activity with a Single Tetracycline-regulatable Plasmid Vector on HeLa Cells HeLa细胞tk基因载体系统细胞活性四环素调控pcDNA3.1To construct a single tetracycline-regulatable plasmid vector based on the double tetracycline-regulatable plasmid .....
关键词：纳米超声造影剂；靶向；人上皮生长因子受体2；单纯疱疹病毒胸苷激酶 doi：10.3969/j.issn.1002-266X.2021.16.005 中图分类号：R445.1文献标志码：A文章编号：1002-266X（2021）16-0020-04 Preparation of HER2-targeted nano-ultrasound contrast agent carrying HSV-TK gene and with nuclear ...
自杀基因系统靶向治疗放射治疗联合应用自杀基因疗法(suicide gene therapy)又称为酶药物前体法(enzyme prodrug therapy),自1986年首次报道单纯疱疹病胸苷激酶(herpeslsimplex virus-thymidine kinase,HSV-TK)因可提高抗病毒药物更昔洛韦(gancyclovir,GCV)对肿瘤细的杀伤敏感性后,自杀基因疗法就成为众多研究者争先探索焦点....
关键词 胶质瘤 凋亡 基因治疗 环丙氧苷 中图号 R73-35 + 4 GanciclovirInducesApoptosisofRatC6GliomaCellTransducedwithHSV-tkGene △ MaWenbin # ChenSongshen * RenZuyuan WangWeijun ZhangJinqiu * SuChangbao WangRenzhi LiYongning (DepartmentofNeurosurgery,PUMCHospital,CAMSandPUMC,Beijing100730,China) Object...