Insertional and terminal rearrangements generate a class of aneuploid progeny that carry a duplication but no deficiency, and this results in asci with 6 black and 2 white ascospores. This method has been used to identify many 展开 年份: 2006 ...
Conserved elements are stretches of DNA sequence that are under purifying selection. That means mutations leading to a change of function in this part of the DNA are detrimental to the organism and will not become fixed in the genome, but rather discarded by natural selection. The level of ...
Genome studies and molecular genetics - We know the sequence, how do we identify the function? Editorial overviewPseudoleskea artariaethermophilous bryophytesdistributionecologyItalyA bibliography of all studies using characters of DNA sequences to address questions pertaining to the systematics of ...
They occur with high frequency by chance in genomic sequences and are therefore hard to identify as functional motifs in vivo. However, experimental evidence suggests that we miss crucial cis-regulatory information if we ignore low-affinity motifs [12,83,84]. It is therefore important to ...
"What I wanted to do in this research, together with my colleagues, was to identify the original viral genome, because the virus mutates, it changes and you get variants arising. All these mutations have happened without anybody realizing a disease is among us," h...
To better understand this protein, you want to identify candidate CTCF binding sites in human chromosome 21. Using a previously published model of the CTCF binding motif (Fig. 1a)2, each 20 nucleotide (nt) sub-sequence of chromosome 21 can be scored for its similarity to the CTCF motif. ...
CpG islands (CGIs), clusters of CpG dinucleotides in GC-rich regions, are often located in the 5' end of genes and considered gene markers. Hackenberg et al. (2006) recently developed a new algorithm, CpGcluster, which uses a completely different mathema
Being able to describe the DNA sequence allows scientists to identify important differences between individuals. 通过描述 DNA 序列,科学家们可以确定个体之间的重要差异。 These unique differences have become the basis for what is known from our DNA fingerprint. ...
The snapclust.choose.k function was used to identify the optimal number of clusters (K) based on the Bayesian information criterion (Schwarz 1978) for the reproducing individuals in the year 2015. Overall comparison of dispersal distances of breeding females and males was conducted with the ...
Another simple method to identify on-target gene edits is to use enzymatic assays followed by gel analysis. The T7EI enzyme is used for this purpose. T7EI does not show the actual sequence composition of the edited region but can indicate that a change in the genomic DNA sequence has occu...