The purpose of this article is to set forth our approach to diagnosing and managing the thalassemias, including β-thalassemia intermedia and β-thalassemia major. The article begins by briefly describing recent advances in our understanding of the pathophysiology of thalassemia. In the discussion on...
The purpose of this article is to set forth our approach to diagnosing and managing the thalassemias, including 尾-thalassemia intermedia and 尾-thalassemia major. The article begins by briefly describing recent advances in our understanding of the pathophysiology of thalassemia. In the discussion on...
However, in sickle cell disease and beta thalassemia, people have faulty versions of the adult gene. Casgevy reverses the switch to adult hemoglobin so that patients can continue using their fetal hemoglobin gene instead. One form of inherited blindness may be among the next disorders treated ...
But keep in mind that a single test isn’t enough to diagnose anemia. Doctors will interpret a hemoglobin value, taking into account a person’s medical history and other test results, such as RBC, hematocrit, and red blood cell indices. A result that is slightly lower may not be of med...
Rachmilewitz EA, Giardina PJ. How I treat thalassemia. Blood. 2011; 118(13): 3479-3488.Rachmilewitz EA, Giardina PJ. How I treat thalassemia. Blood. 2011;118(13):3479-3488Rachmilewitz, E.A. and P.J. Giardina, How I treat thalassemia. Blood, 2011. 118(13): p. 3479-88....
Introduction to a How I Treat series on sickle cell disease and thalassemia - ScienceDirectThomas D. Coates Associate Editor, Blood