alpha] thalassemiagene mappinghemoglobinmean corpuscular hemoglobinhemoglobin EpgApplication of the technique of gene mapping has made possible accurate assessment of the defect in cord blood samples obtained in a Sydney teaching hospital. Results showed a 5.2% incidence of the haplotype in the population...
alpha-Thalassaemia trait should be considered in all patients of 'high-risk' ethnic origins with a blood picture suggestive of beta-thalassaemia trait but in whom the levels of Hb A2 and Hb F are within normal limits. 展开 关键词: Humans Thalassemia Fetal Hemoglobin Blood Cell Count Infant, ...
Detection of alpha-thalassemia in beta-thalassemia carriers and prevention of Hb Bart’s hydrops fetalis through prenatal screening. Haematologica. 2006;91(5):649–51. PubMed Google Scholar King AJ, Higgs DR. Potential new approaches to the management of the Hb Bart’s hydrops fetalis ...
[Rapid detection of alpha-thalassemia of Southeast Asian deletion by polymerase chain reaction and its application to prenatal diagnosis]. Objective To establish a rapid and simple polymerase chain reaction(PCR) method for detecting 伪 thalassemia of Southeast Asia deletion,and apply it to the... W...
YuDepartmentYangDepartmentDong-ZhiDepartmentLiDepartmentPingDepartmentHeDepartmentInformaworldHemoglobinYang Y, Li DZ, He P. A Program on Noninvasive Prenatal Diagnosis of alpha- Thalassemia in Mainland China: A Cost-Benefit Analysis. Hemoglobin. 2016;40(4):247-249. 80. Vrecenak JD, Pearson EG, ...
Confirmation of the validity of using birth MCV for the diagnosis of alpha thalassemia trait.doi:10.4081/hr.2009.e20HbBartshighperformanceliquidchromatographyMCHMCVThirty-four blood samples of neonates in Dubai, UAE, with an MCV below 90 fL were checked by high performance liquid chromatography (...
6. Prenatal gene diagnosis of alpha-thalassemia 地中海贫血产前羊水基因诊断 www.ilib.cn 7. Prenatal gene diagnosis of hemophilia 血友病的产前基因诊断 www.ilib.cn 8. Primarily Application of FNRBCs in DMD Prenatal Gene Diagnosis 胎儿有核红细胞在DMD产前基因诊断中的应用 www.ilib.cn©...
The thalassemias can be defined as α- or β-thalassemias depending on the defective globin chain and on the underlying molecular defects. The recognition of carriers is possible by hematological tests. Both α- and β-thalassemia carriers (heterozygotes) present with microcytic hypochromic parameters...
By using restriction fragment length polymorphisms (RFLP) as linkage markers and family study, prenatal gene diagnosis in 4 cases of β~thalassemia was made successfully. Three cases were diagnosed with RFLP, 2 being diagnosed as heterozygotes and 1 as homozygote of β-thalassemia, the latter bein...
alpha-Thalassemia (alpha-thal)- -~(JS) deletionmolecular analysisprenatal diagnosisα-Thalassemia (α-thal) is a very common single gene hereditary disease caused by large deletions or point mutations of the α-globin gene cluster in tropical and subtropical regions of the world. Here, we report...