In multiple myeloma, IFN has been demonstrated to reduce plasmacells growth by down-regulating the IL6 production, with a synergic action with melphalan and corticosteroids in reducing the monoclonal component. IFN has also been used as maintenance after autologous transplantation before introduction in...
This approval was granted following a randomised phase 3 study that reported that the combination of bendamustine and prednisone was superior to melphalan and prednisone in patients with previously untreated MM (Ponisch et al., 2006). Bendamustine is currently under investigation in clinical trials ...
The European Myeloma Network is initiating a prospective study in which pPCL patients will be treated with a novel agent-containing induction regimen, followed by tandem auto-SCT and allo-SCT, the latter involving semi-intensive conditioning with melphalan 140 mg/m2 + fludarabine, as well as novel...
Hodgkin lymphoma is characterized by a high cure rate in the modern era of medicine regardless of stage, but patients suffer from a high risk of comorbidity associated with the administered therapy. The main aim of this review article is to assess and analyze the various comorbidities associated ...