CD47 recognized by its macrophage receptor SIRPα serves as a “don’t eat-me” signal protecting viable cells from phagocytosis. How this is abrogated by apoptosis-induced changes in the plasma membrane, concomitantly with exposure of phosphatidylserine
an important water-soluble vitamin that isessentialfor DNA synthesis, red blood cell production and maintaining the health of the nervous system. Unfortunately, many vegans and vegetarians are at a higher risk for deficiency, as vitamin B12 is found primarily in animal products and select fortified...
Most micro-organisms can easily be cultivated either in cell-free medium or in cell cultures. Important to note is that any drug action on the micro-organism should be discriminated from aspecific cell toxicity, necessitating the inclusion of a parallel evaluation in host cell lines (cytotoxicity...
These Littmann stethoscope models can pick up sounds as faint as fetal heart beats just six weeks into a pregnancy. While their most common use is in detecting heart and breath sounds, they can also be crucial tools in detecting abnormalities in digestive and venous systems [source: EoS]. Ste...
Currently, there is a high demand for efficient pig embryo cryopreservation procedures in the porcine industry as well as for genetic diversity preservation and research purposes. To date, vitrification (VIT) is the most efficient method for pig embryo c
Recently MEIS1 emerged as a major determinant of the MLL-r leukemic phenotype. The latest and most efficient drugs effectively decrease the levels of MEIS1 in cancer cells. Together with an overview of the latest drugs developed to target MEIS1 in MLL-r
Thus, we felt it worth testing whether the analogous membrane proximal region of the GRK2 RH domain might also play a role in receptor binding. When the kinase domain of GRK2 is superimposed onto those of GRK1/GRK5, the proposed receptor interacting regions in GRK1 and GRK5 are in ...
FTSFICS Testing Server FTSFlight Termination Subsystem FTSFile Transfer Service/System FTSFiscal Transparency Seminar(IMF) FTSFiber-Optic Test Set FTSFriendship Through Sports FTSFlying Tippler Society of the USA(est. 1987) FTSFree Trade Syndicate(gaming alliance) ...
A bronchoscopy is performed to local- Pathophysiology ize and control the plat of bleeding. This is composed of two licity, protein binding, ventilation, perfusion, oxygenation, layers the cilia arising from the columnar epithelium and ageing, lung pathology, and co-administration of other the ...
Since the only alteration seen in the majority of individuals with a HFE mutation is high blood iron levels, the disease may be recognized coincidentally based on incorrect results of blood tests performed for other indications or when screening family members of patients diagnosed with HC. As a ...