How does p53 work? Regulation by the intrinsically disordered domainstranscription factorintrinsically disordered domainsDNA bindingDNA damagepost-translational modificationsDefects in the tumor suppressor protein p53 are found in the majority of cancers. The p53 protein (393 amino acids long) contains the...
The tumour suppressor gene TP53 is mutated in ~50% of human cancers. In addition to its function in tumour suppression, p53 also plays a major role in the response of malignant as well as nontransformed cells to many anticancer therapeutics, particularly
阅读下面的句子观察画线部分,总结并完善一般现在时的特殊疑问句结构及特殊疑问词的用法。(1)What does he do? [教材 P48](2)How does he go to work? [教材 P50](3)Which job do you want to do? [教材 P53]归纳总结1.一般现在时的特殊疑问句结构++主语++其他?2.特殊疑问词的用法疑问词含义提...
How does the p53 protein protect the body from cancer, and how could the p53 protection mechanism negatively influence longevity? What makes the skin impervious to water? What happens during the malting process in beer? Explain how stickleback armor protects fish from some predators. ...
In general terms, describe how gene therapy would work for ALD. What is the difference between the MyD88-dependent and MyD88-independent pathway of TLRs signaling? How does malignancy relate to cancer? How might the disruption of the cell cycle lead to cancer?
https://forum.synology.com/enu/viewtopic.php?p=533350#p533350 Ash3000k wrote: My DS has two Ethernet ports in LACP link aggregation, would it be possible to remove the link aggregation and use one LAN port for the VPN and the other for everything else, or is it just the router ...
How does rapamycin work? Rapamycin does quite a number of things in the cell, but a lot of its effects [involve] slowing down growth and slowing down cell metabolism, which is why it has an impact on aging. Your grandmother lived to be103 years old. Did she take rapamycin, or was her...
The problem is that it is not IPCF shared memory, but it does not work in Linux environment by putting the bin file of another example project in the SD card.example) LLCE CAN, GPT (General Timer), and so on. Please check the attached file. 0 Kudos Reply ...
What is MDM2 and how does it affect the P53 protein? (A) What factors regulate the release of prolactin? (B) What are the clinical effects of hyperprolactinemia? (C) What are the causes of hyperprolactinemia? (a) What is plasmid addiction? (b) How does it work?
Why might a tumor with mutations in p53 be resistant to radiation therapy? What 2 ways are radioactive tracers used in organisms? What types of environmental problems can result from ionizing and non-ionizing radiation? How does ultraviolet radiation in sunlight affect the epidermis? (briefly both...