2,348 A low APTT value in the absence of anticoagulant therapy indicates an increased propensity for clotting. Some anticoagulant medications, including unfractionated heparin, increase APTT, reflecting prolongation of the time needed for clot formation.2 Prothrombin time (PT) evaluates the function ...
Low-molecular-weight heparin or adjusted-dose warfarin should be selected for high-risk patients, whereas aspirin can be considered in patients at standard risk for venous thromboembolism. Tumor lysis syndrome (TLS) is rare in myeloma (∼ 1%-2%) and typically occurs soon after initiation of ...
The presence of HIT alone does not affect prothrombin time (PT), activated partial thromboplastin time (APTT), or fibrinogen level, but these test values may change due to the use of heparin or as a complication of DIC. As reflections of excessive coagulation activation and thrombus formation,...