Heparin lockLow-dose heparin retentionTemporary hemodialysisBackground: The objective of this study was to assess the impact of heparin concentration retained in temporary double-lumen catheters on bleeding risk. Methods: Activated partial thromboplastin time (aPTT) was measured in patients hemodialyzed ...
Both protamine and Neutralase reversed heparin-mediated increases in aPTT (>300 seconds to 26-35 seconds) and TCT (>300 seconds to 29-56 seconds) to values that were not different from saline-treated, nonheparinized animals. Thrombus weight in the nonheparinized saline group was 62+/-7 mg;...
Low molecular weight heparin (LMWH) and unfractionated heparin (UFH) are recommended by the international society for thrombosis on hemostasis (ISTH), American Society of Hematology (ASH) for the treatment of thrombotic events associated with SARS-CoV-2 infection. Particularly, LMWH has a stronger...
Those studies demonstrated more marked thrombocytopenia, an evident reduction of platelet aggregation response, a significant increase in activated partial thromboplastin time (APTT) and a reduction of the albumin/globulin ratio in dogs with clinical leishmaniosis co-infected with E. canis [49,50,51]....
Pre-heparin APTT was the only factor associated with an increase in filter life (p = 0.035). The hazard rate for filter failure was 0.049/h (95% confidence interval 0.04 to 0.06), the range of time until filters failed was 1.8 to 78.5 h. Proximally administered dilute heparin is not ...
The two forms of TFPI1-161 given in the higher doses showed a significantly greater increase of anti-Xa activity, but with a shorter duration compared to LMWH (1.7-1.9 vs. 0.9 anti-Xa IU/ml). Activated partial thromboplastin time (aPTT)-analysis revealed that only LMWH (52 s) caused a...