全部来源 求助全文 onAcademic 相似文献Accurate determination of rivaroxaban levels requires different calibrator sets but not addition of antithrombin Recovery of controls was ± 10% of target valu- es in all assays with exception of the COAMATIC® Heparin assay using the medium and low control ...
Canada Summary Laboratory monitoring is widely recommended to measure the anticoagulant effect of unfractionated heparin and to adjust the dose to maintain levels in the target therapeutic range.The most widely used laboratory assay for monitoring unfractionated he- parin therapy is the activated partial ...
For example, APTT ratios at 0.5 IU/ml heparin increased up to eight‐fold in the presence of ‘therapeutic’ levels of aprotinin (200 KIU/ml) and this effect was even more pronounced at higher heparin levels. The activator used did not significantly influence...
Heparin has generally been used as an anticoagulant during plasmapheresis. In this study plasma heparin levels were studied in nine patients before double ... S.,Hosokawa,A.,... - 《International Journal of Artificial Organs》 被引量: 0发表: 2018年 Dosage monitoring of low molecular weight hep...
CanadaSummaryLaboratory monitoring is widely recommended to measure theanticoagulant effect of unfractionated heparin and to adjust thedose to maintain levels in the target therapeutic range.The mostwidely used laboratory assay for monitoring unfractionated he-parin therapy is the activated partial thromboplast...
aPTT is used to screen for bleeding tendencies and to monitor heparin therapy; it is increased in coagulation factor deficiencies (factors V, VIII, IX, X, XI, XII), DIC, Hodgkin lymphoma, hypofibrinogenemia, leukaemia, cirrhosis, vitamin K deficiency, von Willebrand’s disease, and in drug ...
The ETP-based test was influenced most by free protein S and free TFPI levels. In both tests FXa formation plays a major role, as the effect of FVIII and TFPI on the tests seems to be executed via FXa. The ETP-based test was also strongly influenced by oral contraceptive use, even ...
Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays aPTT was measured using two whole blood methods (Free oscillation rheometry (FOR) and Hemochron Jr (HCJ)) and an optical ...
Partial correction of both PT and APTT was demonstrated on mixing studies, with presence of heparin excluded. Intrinsic factor assays showed universal reduction, with Bethesda assay failed to identify an inhibitor. Extrinsic factors and von Willebrand assays were normal. LA testing showed a moderate ...
We established an aPTT heparin therapeutic range (HTR) corresponding to therapeutic anti-Xa levels for continuous intravenous UFH administration, and used appropriate monitoring to determine if an adequate dose of UFH was applied. A total of 134ex vivosamples were obtained from 71 patients with a ...