levels impairs its antithrombotic efficacy and that high unfractionated heparin levels can cause excessive bleeding, lab- oratory monitoring is recommended to measure the anticoagu- lant effect of unfractionated heparin and to adjust the dose to maintain levels in the target therapeutic range (1, 6)...
80 Samples from 2 patients were excluded due to absence of fibrinogen and/or INR measurements on the same day. The mortality in patients with prolonged APTT but normal fibrinogen levels and normal INR (N=29; due to FXI/FXII-consumption) was significantly lower compared to the remaining 28 ...
aPTT is used to screen for bleeding tendencies and to monitor heparin therapy; it is increased in coagulation factor deficiencies (factors V, VIII, IX, X, XI, XII), DIC, Hodgkin lymphoma, hypofibrinogenemia, leukaemia, cirrhosis, vitamin K deficiency, von Willebrand’s disease, and in drug ...
The HTR were 58.3s~124.4s and 42.8s~69.2s of APTT ACTIN reagent and APTT ACTIN FSL reagent respectively,two patients with heparin were monitored and the APTT results showed similar trend between two reagents. Conclusions APTT ACTIN FSL reagent has good performance on CS5100 and CA7000 analyzers...
Diabetic patients have elevated levels of fibrinogen and factors in the intrinsic pathway, which are determinants of APTT [6]. PT and APTT tests are ... R Barazzoni,M Zanetti,G Davanzo,... - 《J Clin Endocrinol Metab》 被引量: 80发表: 2000年 The anticoagulant activity of heparin: Measur...
Activated partial thromboplastin time (APTT) 来自 Semantic Scholar 喜欢 0 阅读量: 6 作者: L Poller 展开 DOI: 10.1007/978-94-011-4722-4_5 年份: 1999 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Semantic Scholar 通过文献互助平台发起求助,成功后即可免费获取论文全文。 请先登入...
The study also examined the effect of actual body weight (ABW), body mass index (BMI), smoking, concomitant intravenous glycerine trinitrate, age, gender and creatinine levels, individually, on the time taken to attain a therapeutic aPTT in acute coronary syndrome (ACS) patients receiving a ...
For example, APTT ratios at 0.5 IU/ml heparin increased up to eight‐fold in the presence of ‘therapeutic’ levels of aprotinin (200 KIU/ml) and this effect was even more pronounced at higher heparin levels. The activator used did not significantly influenc...
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activitydoi:10.1007/s11239-024-03048-0Hospitalized patients may exhibit discordance in aPTT and anti-Xa activities while on UFH. In this study, 59% of ICU patients that received UFH had discordant levels. ...
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activity doi:10.1007/s11239-024-03048-0Hospitalized patients may exhibit discordance in aPTT and anti-Xa activities while on UFH. In this study, 59% of ICU patients that received UFH had discordant levels. ...