肺血栓栓塞症患者肝素剂量浓度与aptt关系160;160;160;160;160;关键词 肝素活化部分凝血酶原时间肺栓塞抗凝治疗摘要目的 以13 uh183;kg作为肺栓塞患者肝素抗凝起始量,分别研究该起始量下肝素剂量及血浆肝素浓度与活化部
One of the main advantages of anti‐Xa relies on its hypothesized standardization, with a unique therapeutic range (0.30‐0.70 IU/ml) for all reagents, whereas APTT is influenced by numerous preanalytical and analytical parameters not related to the anticoagulant activity of UFH. Methods The aim ...
A therapeutic range for the aPTT of 1.5 to 2.5 times the control value has become widely accepted, but the evi- dence supporting this range is weak and the clinical validity of using the aPTT for predicting thrombotic or bleeding events has Eikelboom, Hirsh: Monitoring unfractionated heparin ...
The American College of Chest Physicians (ACCP) recommends that the activated partial thromboplastin time (aPTT) therapeutic range for unfractionated heparin be defined as the aPTT corresponding to a heparin concentration of 0.3-0.7 micro/mL by heparin anti-factor Xa assay. This recommendation suggests...
rabbitplasmaandfleshrabbitplasmainthetestofheparinpotencyusingactivatedpartialthromboplastintimemethod(APTTmethod).Methods:Re—ferringtoAP111’methodinBritishPharmacopoeia.thecoagulationtimewasanalyzedbycoagulometertostudythelinearityrange,repeatability,reliability,precisionofAP11T,aswellastheexpirationtimeoffrozenplasma.Re...
Some samples (for the reference range and ERE) were aliquoted and stored frozen at-20[degrees]C until testing was performed. Stago Start Max analyser validation and early reaction errors (ERE) in haemostasis testing at Wellington SCL Laboratory tests revealed significantly prolonged APTT (74.5 s)....
同时比 较 2 种试剂对凝血因子,LA 检测的敏感性,建立普 通肝素治疗范围( heparin treatment range,HTR) ,为 临床和实验室使用新试剂提供参考. 1 材料与方法 1.1 样本 收集北京协和医院门诊,住院患者及健 康体检者枸橼酸钠( 109 mmol / L) 抗凝静脉血标本, 并于采集后 1 h 内在 2 500×g 条件下离心 ...
APTT is a sensitive and commonly used screening test for endogenous clotting systems, which can also be used as quantitative test of endogenous coagulation factors to detect serum factors other than VII, especially for the test of factor VIII, IX, XI, XII and prekallikrein. Besides, APTT test...
Plasma from normal volunteers and patients on stable warfarin therapy was heparinised in vitro and the APTT measured using a range of calcium chloride concentrations. A striking difference was noted between the reagent systems using kaolin as an activator compared with those using ellagic acid. With...
APTT therapeutic range for monitoring unfractionated heparin therapy. Significant impact of the anti-Xa reagent used for correlation: COMMENTdoi:10.1111/jth.15356Michael J. KovacsDepartment of Medicine Western University London ON CanadaAlejandro Lazo-Langner...