HO-1 inhibitor 1 is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM. ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商,致力于为广大科研、商业实验室的科学研究者提供高品质的产品与技术服务,不断促进生命科学领域的新技术发展。
et al.. Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer. Clin Cancer Res An Off J Am Assoc Cancer Res (2018) 24(7):1617–28. 10.1158/1078-0432...
By targeting hypoxia-induced HO-1, we have tested the effect of a novel acetamide-based HO-1 inhibitor (VP18/58) on GBM progression. Results have demonstrated that hypoxic conditions induced upregulation and nuclear expression of HO-1 in a cell-dependent manner related to malig...
HO-1-IN-1;HO-1 inhibitor 1;Heme Oxygenase-1-IN-1;Heme Oxygenase-1-IN-1, 10 mM in DMSO;1H-Imidazole, 1-[4-(4-bromophenyl)butyl]-;Heme Oxygenase 1 IN 1,inhibit,Inhibitor,Reactive Oxygen Species,HO-1,Heme Oxygenase1IN1 CBNumber: CB25419753 Molecular Formula: C13H15BrN2 Molecular...
METHODS: Rats were randomly divided into normal group, model group, Liuwei dihuang pills group (14 g/kg, ig, s.i.d) and HO-1 inhibitor zinc protoporphyrin (ZPP, 10 μmol/kg, ip, q.o.d)+Liuwei dihuang pills (14 g/kg, ig, s.i.d) group, with 12 rats in each group. Except...
ho-1-in-1 hydrochloride ?is a heme oxygenase 1 (ho-1) inhibitor with an ic50 of 250 nm.? 价格:¥电议型 号:T11580L产 地:美洲 T72827Nrf2/HO-1-IN-1;化合物 Nrf2/HO-1-IN-1Nrf2/HO-1-IN-1 nrf2/ho-1-in-1 is a potent nrf2/ho-1 pathway inhibitor, with an ic 50 value of ...
(IL-1β) levels in cell supernatants were detected by ELISA; the NRF2-specific inhibitor ML385 was used to inhibit the NRF2 pathway; ALP staining and ALP activity were used to detect the markers of early osteogenic differentiation; qRT-PCR was used to detect the gene expression of ALP, ...
(a Nrf2 inhibitor), 60 μmol/L berberine and erastin in the cells to explore the protective mechanism of berberine against erastin-induced ferroptosis in the neuronal cells. Results Treatment with 0.5 μmol/L erastin significantly lowered the viability of HT22 cells (P<0.05) and increased the ...
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HO-1-IN-1 (Compound 2) is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM[1]. [1]. Floresta G, et al. Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis. Bioorg Chem. 2018 Dec;81:334-339. ...