Symptoms gradually progressed over two weeks and he was transferred to Intensive care unit for persistent hypotension and confusion. Physical exam was remarkable for 8 x 10 cm ulcer with clear base but no erythema or discharge on the right scapular area, and mild basal crackles on chest ...
Case Presentation: We present four cases of secondary HLH in adults with varying presentations with a variety of underlying triggers including EBV infection, T cell lymphoma and blinatumomab therapy. Conclusion: HLH has multifaceted clinical presentations with often non-specific signs and symptoms that ...
(ED) with a three-day history of flu-like symptoms, fever, erythematous rash, widespread joint pain, nausea and chills. Acute Dengue virus infection was confirmed with serum polymerase chain reaction (PCR) testing. On day two, she was admitted to intensive care for multi-organ support ...
HLH-2004 方案.pdf,Histiocyte Society HLH-2004 Hemophagocytic Lymphohistiocytosis Study Group Treatment Protocol of the Second International HLH Study 2004 Start of the Study: January 2004 Chairman: Jan-Inge Henter, M.D., Ph.D., Stockholm, Sweden HLH-2004
Neurologic symptoms were reported in 33% of the patients before therapy start and a history of recent infection at the onset of HLH symptoms in 45%. Table 2. Patient characteristics in history, clinical findings, and laboratory parameters before start of therapy in all patients Patient subgroup...
And it should not be systemic lupus erythematosus, because no obvious symptoms could be found in physical examination. The central nervous sys- tem was also normal. Together with the identification of 1 bp deletion in exon of SH2D1A, a diagnosis of HLH could be accepted. However, it is ...
Case Presentation: We present four cases of secondary HLH in adults with varying presentations with a variety of underlying triggers including EBV infection, T cell lymphoma and blinatumomab therapy. Conclusion: HLH has multifaceted clinical presentations with often non-specific signs and symptoms that ...
Male, 30 FINAL DIAGNOSIS: Hemophagocytic lymphohistiocytosis (LHL) Symptoms: Abdominal pain fever hypotension pancytopenia- Clinical Procedure:- Special... H David,Gonzalo,Guillermo,... - 《Journal of Pediatric Hematology/oncology》 被引量: 16发表: 2007年 ...
For the clinician, the most important step towards diagnosing HLH is to include it in the list of potential differential diagnoses. The leading triad of symptoms consists of prolonged fever of unknown origin, hepatosplenomegaly, and bi- or pancytopeniae. A known family history or known gene ...
Epstein-Barr virus (EBV) infection may present with fulminant constitutional symptoms, cytopenia(s), and systemic lymphadenopathy, raising clinical suspicion for lymphoma and prompting lymph node and bone marrow biopsies. At the microscopic level, the histopathologic findings in cases of acute EBV ...