Solomon et al (Human Immunology 34: Suppl.1:45 (1992) claimed that the expression of HLA-DR3 gene in Afro-American renal recipients was beneficial for the graft survival. The present study was undertaken to address this issue. A retrospective analysis of the SEOPF multicenter database on ...
(P<0. 05).Conclusion:HLA—DR3 couldbe 山esusceptiblegeneofAD,whileHLA—DR6couldbetheresistantgeneofAD.Theresultsindicatethatpeoplewith HLA—DR3arereliabletoAD,whilepeoplewithHLA—DR6arenot.Itissuggestedthatthespecificimmunoreactivitytomite, whichisinducedbytheADpatientswithHLA-DR3,mighttrigerthe...
Process for detecting HLA-DR3 genetype of AD patients by employing PCR techniqueThe invention relates to a method for detection of HLA-DR3 genotype of AD sufferers by means of PCR technology employing the denaturation, annealing, extension, circulation of the DNA reagent of the AD suffer to ...
Relationship between HLA-DR gene polymorphisms and outcomes of hepatitis B viral infections:A meta-analysis AIM:To assess the rigorous relationship between human leukocyte antigens(HLA)-DR alleles and outcomes of hepatitis B virus(HBV) infections by means of meta... Ze-Hui,Yan,Yi,... - 《Wor...
HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB). The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 enc...
The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain ...
Polymorphic restriction endonuclease sites within the HLA-DR alpha gene have been defined, localized, and used as genetic markers in the analysis of suscep... D,Stetler,F,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 60发表: 1985年 The ...
HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB). The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 enc...
It is concluded that a gene or genes responsible for type III and IV allergic reactions leading to the disease is associated with HLA-DR3. The increase of Bf S allotype and low mean factor B concentrations, however, can be explained by the strong linkage disequilibrium between Bf 5 and ...
HLA-DRβ gene DNA polymorphisms revealed by Taq I correlate with HLA-DR specificities Human genomic DNA digested with restriction endonuclease Taq I was hybridized with cDNA probes for DRβ and DQβ, for correlation of restriction fragment l... MRJ Kohonen-Corish,SW Serjeantson - 《Human Immuno...