The polymorphie second exon of HLA-DRB gene was amplified by sequence-specific primer polymerase chain reaction (SSP/PCR) methods. All patients had their serum IgE(total and spscifie) antibody levels by RAST, bronchial reactivity assessed by methaeholine brocho-provocation test and/or hroncho...
1) HLA-DRB gene 人白细胞抗原DRB基因 2) Human albumin 人白蛋白 1. To explore a new lyophilized preservation methods for human platelets, platelets were pre-treated with aldehyde, human albumin or trehalose was added to the system of condensed cooling as protectant to stabilize the structure of...
1) HLA-DRB gene HLA-DRB基因 1. To elucidate the underlying mechanism of allergic reaction to penicillins, we explored the relationship between allergic reaction to penicillins andHLA-DRB genetic polymorphism, and the correlation betweenHLA-DRB genetic polymorphism and specific IgE antibodies of penici...
Key words: HBV infection; HLA-DRB gene; genotyping; polymerase chain reaction (PCR)▲ 人体感染乙型肝炎病毒(Hepatitis B virus,HBV)后的临床表现形式多样,其预后各不 相同。这与机体对HBV免疫应答(Ir)方式不同有关,而机体的Ir基因位于人主要组织相容性 复合物(即HLA基因)的D区。研究HLA-DR基因型与HBV不...
hla-drb1属于hlaⅡ类β链副记录。II类分子是一种异二聚体,由α(DRA)和β链(DRB)组成,两者都锚定在膜上它在免疫系统中起着中心作用,通过提供来自细胞外蛋白质的肽。Ⅱ类分子在抗原提呈细胞(apc:b淋巴细胞、树突状细胞、巨噬细胞)中表达。β链约为26-28 kDa。它由6个外显子编码。外显子1编码先导肽;外...
Sequencing of alleles of the highly polymorphic, multiple loci HLA-DRB gene family was performed by pyrosequencing using purified DNA from the 11 th Intern... - 《Human Immunology》 被引量: 40发表: 2004年 Nomenclature for factors of the HLA system, update March 2000. WHO Nomenclature Committee...
Gene ID (NCBI) 3125 Alternative Names HLA-DRB3; HLA-DR1B; HLA-DR3B; major histocompatibility complex, class II, DR beta 3 Application Notes: The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. ...
genefrequency of HLA-DR6(I3)in GDM women groupcompared withnormal pregnancy(1 I.67%VS 2.5%.P<0.05.RR25.78). WeobservedanincreaseofDR3andDR9 gene 4inGDM women,but thestatistical differenceweren’t significant(8.33%VS3.75%,23.33%VS16.25%,P>O.05).A ...
35, 151-157, 1990 DIRECT SEQUENCING OF A HLA-DRB GENE BY POLYMERASE CHAIN REACTION: SEQUENCE VARIATION IN DRw8 SPECIFICITY Yoshihisa WATANABE,1,* Katsushi TOKUNAGA,e Kazumasa MATSUKI,2 Keiichi OMOTO1, and Takeo JuJI2 1Department of Anthropology, Faculty of Science, University of Tokyo, Bunkyo-...
HLA-DRB1*03, but not the TNFA -308 promoter gene polymorphism, confers protection against fistulising Crohn's disease. Crohn's disease (CD) appears in forms so diverse that it has been hypothesized CD might be a syndrome, with different pathogenic mechanisms leading to the ... G Bouma,AC...