After haplotype reconstruction the HLA-DRB1*07:01-HLA-DQB1*02:02 haplotype was associated with an increased risk. After inferring the HLA-DQA1 alleles the HLA-DRB1*07:01-HLA-DQA1*02:01-HLA-DQB1*02:02 haplotype was associated with the highest risk of asparaginase hypersensitivity (p=1.22x10...
All were HLA-DQB1*06:02-positive. Patients were excluded in case of secondary narcolepsy; pregnancy; other neurological or autoimmune co-morbidities (hay fever and asthma was accepted); major HLA-DQA1*01:02/DQB1*06:02 binding epitopes in prepro-hypocretin To examine if any peptides derived...