HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer. J Clin Oncol 2011;29:667-73.SPRAGGS,... CF Spraggs,LR Budde,LP Briley,... 被引量: 0发表: 0年 T cells infiltrate the liver and kill hepatocytes in HLA-B()57:01-associate...
After haplotype reconstruction the HLA-DRB1*07:01-HLA-DQB1*02:02 haplotype was associated with an increased risk. After inferring the HLA-DQA1 alleles the HLA-DRB1*07:01-HLA-DQA1*02:01-HLA-DQB1*02:02 haplotype was associated with the highest risk of asparaginase hypersensitivity (p=1.22x10...
摘要: Three novel alleles DQA1*01:08, 01:09 and 03:03:02 are described. All are single-nucleotide substitutions.关键词: HLA‐DQA1 novel alleles polymerase chain reaction‐sequence‐based typing DOI: 10.1111/tan.12009 被引量: 11 年份: 2012 ...