Monocytes from C08 were characterized by upregulated level of HLA-DRA and HLA-DRB1, which closely resembled CD14+HLA-DRhigh inflammatory monocyte. C10 monocytes exhibited high expression of S100A family genes, including S100A8 and S100A12, along with low expression of HLA-DR, reminiscent of HLA...
The TruSight HLA Sequencing Panel Library Preparation protocol provides: } A single assay and workflow to obtain ultra-high-resolution sequencing of 8 HLA Loci (Class I HLA-A, -B, -C; Class II HLA-DRB1/3/4/5, -DQA1, -DQB1, ...
Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1. Diabetes Obes Metab. 2009;11:46–52. https://doi.org/10.1111/j.1463-1326.2008.01002.x. Article PubMed PubMed Central Google Scholar Pujol-Borrell R, Todd I, Doshi M, Bottazzo GF,...
Positive internal control amplicon with primer sequences (F: 5′-TGCCAAGTGGAGCACCCAA-3′; R: 5′-GCATCTTGCTCTGTGCAGAT-3′) giving a 779 bps product (HLA-DRB1 intron sequence) was run with each sample to check for PCR failure. SNP selection and Genotyping. Three SNPs were selected ...
专利名称:抗hla-dr抗体的制作方法 技术领域:本发明涉及可识别人类白细胞抗原-DR(HLA-DR)的抗HLA-DR抗体,该抗体是与免疫性相关的细胞膜分子。此外,本发明涉及所包含有效成分为抗HLA-DR抗体的下列两类药剂(1)用于由HLA-DR表达细胞所引起疾病的预防或治疗性药剂,尤其是用于恶性肿瘤的治疗性药剂;和(2)用于由HLA-...
The study identified 28 HLA-A, 41 HLA-B, 21 HLA-C, 26 HLA-DRB1, and 25 HLA-DQB1 alleles. Among HLA-A alleles, A∗11:01:01, A∗24:02:01, and A∗33:03:01 were most frequent. For HLA-B, B∗15:02:01, B∗46:01:01, B∗58:01:01, B∗40:01:02, B∗38:...
Positive internal control amplicon with primer sequences (F: 5′-TGCCAAGTGGAGCACCCAA-3′; R: 5′-GCATCTTGCTCTGTGCAGAT-3′) giving a 779 bps product (HLA-DRB1 intron sequence) was run with each sample to check for PCR failure. SNP selection and Genotyping Three SNPs were selected for ...