The classical human leukocyte antigen (HLA)-DRB1*03:01 and HLA-DRB1*04:01 alleles are established autoimmune hepatitis (AIH) risk alleles. To study the immune-modifying effect of these alleles, we imputed the genotypes from genome-wide association data i
Three haplotypes were mainly associated with jSLE in Caucasian participants: HLA-DR2h (HLA-DRB1∗15:01∼DQA1∗01:02∼DQB1∗06:02, affecting 33.8 %), HLA-DR3h (HLA-B∗08:02∼DRB1∗03:01, affecting 30.4 %), and HLA-DR7h (HLA-DRB1∗07:01∼DQA1∗02:01, affecting ...
机译:台湾人保守的HLA-A * 02:01-B * 13:01-DRB1 * 14:01:03单倍型与DRB1 * 14:01:03和DRB1 * 14:54之间可能存在紧密的关系。 3. Recognition of the three deduced probable human leukocyte antigen haplotypes in association with HLA-A?31:30 (A?31:30-B?15-DRB1?14) and HLA-B?40:55 (...