Robinson, J., et al.., IMGT/HLA Database - a sequence database for the human major histocompatibility complex. Tissue Antigens, 2000. 55(3): p. 280-287.Robinson J, Malik A, Parham P, Bodmer JG, Marsh SGE. IMGT/HLA database - sequence database for the human major histocompatibility...
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66. The final dataset included over 200,000 quantitative BA measurements across peptides and 190 MHC-I alleles (Supplementary Data 7). The IPD-IMGT/HLA database was used to retrieve the MHC molecule sequences. The following equation was used to convert the peptide–MHC binding affinities ...
Side chains that come close to the peptide can be identified and then examined on the sequence alignments at IMGT/HLA database. Anyone can download software and sequence. Have fun! Effects of heterogeneity of isoform pairingAs an MHC class II antigen-presenting receptor, DQ functions as a ...
HLAscan is an alignment-based program that determines haplotypes taking read distribution into account. The software performs alignment of reads to HLA sequences from the international ImMunoGeneTics project/human leukocyte antigen (IMGT/HLA) database. ...
These data strongly implicate the involvement of a specific HLA class I polymorphic sequence in the DQβ0603:DQα0103 antibody reactivity. Fig. 3: Reactions of DQβ0603:DQα0103 specific sera to recombinant DQβ0603:DQα0103 protein purified from LCLKO with A*02:01 or C*16:01 gene. The...
在本实施例中,pcr引物设计所需要的hla外显子序列来源imgt/hladatabase,网址:http://www.ebi.nc.uk/ipd/imgt/hla/。引物设计采用primerpremier6.0软件,设计的引物在imgt数据库中进行比对,确认该组引物能特异性地对所需片段进行扩增或测序。 所述引物由上海英骏生物技术有限公司合成,具体序列如前所述。
The primary database within the IPD project is the IPD-IMGT/HLA Database, which provides a locus-specific database for the hyper-polymorphic allele sequences of the genes in the HLA system, also known as the human Major Histocompatibility Complex. The IPD-IMGT/HLA Database was first released...
Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma. Coeliac disease is precipitated in susceptible subjects by ingestion of wheat gluten or gluten related prolamins from some other cereals. The disease is strongly ...
To make the HLA genomic sequence database, execute these unix commands:wget ftp://ftp.ebi.ac.uk/pub/databases/imgt/mhc/hla/fasta/A_gen.fasta wget ftp://ftp.ebi.ac.uk/pub/databases/imgt/mhc/hla/fasta/B_gen.fasta wget ftp://ftp.ebi.ac.uk/pub/databases/imgt/mhc/hla/fasta/C_gen....