colf DNA polymerase I and more recently with the thermostable Taq DNA polymerase, to determine the allelic sequence diversity of the HLA class II genes (HLA-DR尾, HLA-DQ伪, HLA-DQ尾, and HLA-DP尾).doi:10.1007/978-1-349-20235-5_16Henry A. Erlich...
Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease Genes Immun. 2008; 9(4): 358-63.Zeitlin AA, Heward JM, Newby PR, Carr-Smith JD, Franklyn JA, Gough SC, et al. Analysis of HLA class II genes in Hashimoto's thyroiditis reveals ...
HLA class II genes are composed of three closely linked subregions encoding the polymorphic HLA class II molecules HLA-DP, -DQ, and -DR19. We investigated whether hNE cleaves recombinant (r) HLA class II molecules rHLA-DP α1, -DP β1, -DQ α1, -DQ β1, -DR α, and -DR β1....
HLA class II genes associated with REM sleep behavior disorder. Ann Neurol 1996;39:261-263.Schenck CH,Garcia-Rill E,Segall M,et al.HLA class Ⅱ genes associated with REM sleep behavior disorder[].Annals of Neurology.1996Schenck CH,Garcia-Rill E,Segall M,et al.HLA class Ⅱ genes ...
Association of HLA class II genes with systemic sclerosis in Koreans . J Rheumatol 2001; 28 :1577–83Kang SH, Park MH, Song EY, Kang SJ, Lee EB, Song YW, Takeuchi F. Association of HLA class II genes with systemic sclerosis in Kore- ans. J Rheumatol 2001; 28: 1577-83....
Expression of HLA class II genes is coordinately regulated by cis -acting elements present in their promoter regions immediately upstream from the 5' end of their tranccription start sites. Trans -acting factors from the nuclear proteins of the cell are able to positively or negatively regulate ...
HLA-II分子结合抗原肽模式图 孙汶生教授高教版-2010-秋-朱 31 Antigen-binding cleft of dimeric class II DR1 molecule 孙汶生教授高教版-2010-秋-朱 32 3.HLA-II : 主要分布于APC细胞、胸腺上皮细胞和活化 的T细胞表面 可溶性形式 IFN-γ、TNF- 和GM-CSF等可刺激HLA-II 分子的表达 孙汶...
In addition, the stimulatory capacity of these cells was tested in mixed cultures of lymphocytes and spermatozoa, and the levels of RNA homologous to the HLA class I and class II genes were determined. The results obtained using the ELISA indicate that the class I and class II HLA ...
We studied the histocompatibility antigen genesandin addition to, andin 80 Japanese patients with acetaminophen-related SJS/TEN with SOC. We performed polymerase chain reaction amplification followed by hybridization with sequence-specific oligonucleotide probes (PCR-SSO) using commercial bead-based typing ...
We have confirmed that 10F04mc TCR is class II HLA molecular restricted but can be expressed on the surface of both CD4+and CD8+human T cells (Fig.3a). When co-cultured with target cells, 10F04mc TCR-T cells secret cytokines and directly induce target cell lysis (Supplementary Movie1an...