HLA-A2.1 transgenic mice combined with immunologically reconstituted tumour-bearing mice were used to examine the antitumour effect and safety of epitope vaccines. Results We identified novel HLA-A2.1-restricted extracellular matrix protein 1(ECM1)-derived immunodominant epitopes in which LA induced a ...
"Cytotoxic T cell responses in HLA-A2.1 transgenic mice. Recognition of HLA alloantigens and utilization of HLA-A2.1 as a restriction element." J Immunol 142(4): 1366-1371. 3.Vitiello, A., D. Marchesini, J. Furze, L. A. Sherman and R. W. Chesnut (1991). "Analysis of the HLA-...
HLA A2 (A2) transgenic mice are currently being used to compare different vaccination protocols. However, the monitoring of A2 restricted CTL in A2 transgenic mice have been hampered by poor staining efficiency of mouse CTL by A2 tetramers. We demonstrate here that chimeric A2 tetramers containin...
In mice lacking normal class I molecules but expressing an HLA-A2.1/D(b)-beta2 microglobulin single chain (HHD mice), three peptides elicited specific... L Carmon,I Bobilev-Priel,B Brenner,... - 《Journal of Clinical Investigation》 被引量: 99发表: 2002年 Peptide binding to HLA-A2 ...
Identification of HLA-A2 restricted epitopes of glypican-3 and induction of CTL responses in HLA-A2 transgenic mice Xiaoxiao Jin Xiaotao Liu Chuanlai Shen Cancer Immunology, Immunotherapy (2022) Diagnostic utility of p501s (prostein) in comparison to prostate specific antigen (PSA) for the det...
HLA-A2 transgenic mice in the C57BL/6 background were kindly provided by Songdong Meng's lab. HLA-A11 transgenic mice were purchased from Taconic (Model# 9660). HLA-A33 trans- genic mice were generated in our lab by microinjection of the Rosa26 BAC (RP24-85L15 CHORI, Oakland, CA, ...
Saha et al (2009) Stimulatory effects of CpG oligodeoxynucleotide on dendritic cell-based immunotherapy of colon cancer in CEA/HLA-A2 transgenic mice. International Journal of Cancer 124:877 [PubMedID:19035460]Saha et al (2010) Combination of CTL-associated Antigen-4 Blockade and Depletion of ...
The Fusion Protein of CTP-HBcAg18-27-Tapasin Mediates the Apoptosis of CD8(+)T Cells and CD8(+) T Cell Response in HLA-A2 Transgenic Mice. Chen, et al., The fusion protein of CTP-HBcAg18-27-Tapasin mediates the apoptosis of CD8(+)T cells and CD8(+) T cell response in HLA-A2 ...
We have generated a panel of transgenic mice expressing HLA-A*01:03, -A*24:02, -B*08:01, -B*27:05, -B*35:01, -B*44:02, or -C*07:01 as chimeric monochain mo... R Boucherma,H Kridane-Miledi,R Bouziat,... - 《Journal of Immunology》 被引量: 41发表: 2013年 HLA-A, ...
Furthermore, Pospori et al have shown that hematopoietic stem cells expressing a transduced TCR specific for a WT-1 peptide presented by HLA-A0201 are not deleted in the thymus of HLA-A0201–transgenic mice and generate functional memory T cells.63 However, whereas the basis for this lack ...